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Q1CGE3

- LFTR_YERPN

UniProt

Q1CGE3 - LFTR_YERPN

Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

    Catalytic activityi

    L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
    L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

    GO - Molecular functioni

    1. leucyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciYPES377628:GIXK-2679-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
    Alternative name(s):
    L/F-transferaseUniRule annotation
    LeucyltransferaseUniRule annotation
    PhenyalanyltransferaseUniRule annotation
    Gene namesi
    Name:aatUniRule annotation
    Ordered Locus Names:YPN_2609
    ORF Names:YP516_2941
    OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
    Taxonomic identifieri377628 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000008936: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 236236Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000258115Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi377628.YPN_2609.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1CGE3.
    SMRiQ1CGE3. Positions 1-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the L/F-transferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2360.
    HOGENOMiHOG000102325.
    KOiK00684.
    OMAiWSPDPRG.
    OrthoDBiEOG6WX4R3.

    Family and domain databases

    HAMAPiMF_00688. Leu_Phe_trans.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view]
    PfamiPF03588. Leu_Phe_trans. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 1 hit.
    TIGRFAMsiTIGR00667. aat. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1CGE3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRVTQLSSQS FIFPSPELAL REPNGLLALG GDLTAPRLLA AYQRGIFPWF    50
    NPGEMILWWS PDPRAVLFPE DLHISRSMRR FIRHCPYRFT LNHAFADVIS 100
    ACATERDEGT WIGRDVQQAY CQLHALGHAH SLEVWLENEL VGGLYGVAVG 150
    AVFCGESMFS RADNASKSAL MVFCHHFTQH GGELIDCQVL NAHTASLGAV 200
    EIPRNFFLQQ LSQLQFSPLP AECWLPQSLN FSSAMQ 236
    Length:236
    Mass (Da):26,403
    Last modified:July 11, 2006 - v1
    Checksum:i19B93E1B026F2547
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000305 Genomic DNA. Translation: ABG18937.1.
    ACNQ01000017 Genomic DNA. Translation: EEO75056.1.
    RefSeqiYP_648537.1. NC_008149.1.

    Genome annotation databases

    EnsemblBacteriaiABG18937; ABG18937; YPN_2609.
    EEO75056; EEO75056; YP516_2941.
    GeneIDi4124121.
    KEGGiypn:YPN_2609.
    PATRICi18604932. VBIYerPes46733_3117.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000305 Genomic DNA. Translation: ABG18937.1 .
    ACNQ01000017 Genomic DNA. Translation: EEO75056.1 .
    RefSeqi YP_648537.1. NC_008149.1.

    3D structure databases

    ProteinModelPortali Q1CGE3.
    SMRi Q1CGE3. Positions 1-229.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 377628.YPN_2609.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG18937 ; ABG18937 ; YPN_2609 .
    EEO75056 ; EEO75056 ; YP516_2941 .
    GeneIDi 4124121.
    KEGGi ypn:YPN_2609.
    PATRICi 18604932. VBIYerPes46733_3117.

    Phylogenomic databases

    eggNOGi COG2360.
    HOGENOMi HOG000102325.
    KOi K00684.
    OMAi WSPDPRG.
    OrthoDBi EOG6WX4R3.

    Enzyme and pathway databases

    BioCyci YPES377628:GIXK-2679-MONOMER.

    Family and domain databases

    HAMAPi MF_00688. Leu_Phe_trans.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view ]
    Pfami PF03588. Leu_Phe_trans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 1 hit.
    TIGRFAMsi TIGR00667. aat. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
      Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
      J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nepal516.
    2. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
      Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
      Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiLFTR_YERPN
    AccessioniPrimary (citable) accession number: Q1CGE3
    Secondary accession number(s): C4GVV6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3