Q1CF49 (Q1CF49_YERPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-galactosidase PIRNR PIRNR001084
Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084

Gene names

Name:	ganB EMBL EEO75537.1
Ordered Locus Names:	YPN_3054
ORF Names:	YP516_3462 EMBL EEO75537.1

Organism

Yersinia pestis bv. Antiqua (strain Nepal516) [Complete proteome] [HAMAP]

Taxonomic identifier

377628 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	686 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084
Sequence similarities	Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Ontologies

Keywords
Ligand	Metal-binding PIRSR PIRSR001084-3 Zinc PIRSR PIRSR001084-3
Molecular function	Glycosidase PIRNR PIRNR001084 EMBL ABG19381.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular function	beta-galactosidase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton donor By similarity PIRSR PIRSR001084-1
	Active site	314	1	Nucleophile By similarity PIRSR PIRSR001084-1
	Metal binding	122	1	Zinc By similarity PIRSR PIRSR001084-3
	Metal binding	162	1	Zinc By similarity PIRSR PIRSR001084-3
	Metal binding	164	1	Zinc By similarity PIRSR PIRSR001084-3
	Metal binding	167	1	Zinc By similarity PIRSR PIRSR001084-3
	Binding site	118	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	156	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	322	1	Substrate By similarity PIRSR PIRSR001084-2

Sequences

	Sequence		Length	Mass (Da)
	Q1CF49 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: CBDA4617C9775AB4	FASTA	686	78,165
	10 20 30 40 50 60 MSKFPPLSAK VSALLHGADY NPEQWENYPD IIDKDIAMMK QAKCNVMSVG IFSWVKLEPS 70 80 90 100 110 120 EGEYNFSWLD ELIEKLYAAG IHIFLATPSG ARPAWMSQKY PEVLRVGRDR VPALHGGRHN 130 140 150 160 170 180 HCMTSPVYRQ KVRQINQKLA ERYAHHPAVI GWHISNEYGG ECHCHSCQQK FRLWLQDRYQ 190 200 210 220 230 240 TLDNLNEAWW SAFWSHTYSD WSQIESPAPQ GEVSIHGLNL DWRRFNTAQV TEFCSEEAKP 250 260 270 280 290 300 LKAANPELPV TTNFMEYFYD YDYWKLAQVI DFISWDSYPM WHREKDETQL ACYTAMYHDL 310 320 330 340 350 360 MRTLKQGRPF VLMESTPSAT NWQPTSKLKK PGMHILSSLQ AVAHGADAVQ YFQWRKSRGS 370 380 390 400 410 420 VEKFHGAVVD HVGHIDTRVG REVSELGRIL EAMSPVMGSK VDADVAIIFD WESRWAMDDA 430 440 450 460 470 480 EGPRNCGLEY EKTVAEHYRP FWERGIAVDI INADCDLSGY KLVIAPMLYM VREGFAERAT 490 500 510 520 530 540 RFVEQGGQFV ATYWSGIVNE SDLCHLGGFP GPLRPLLGIW SEEIDCLADG ESNQVQGLAG 550 560 570 580 590 600 NKAGLQGPYQ AIHLCDLIHL EGATAVARYR DDFYADRAAV TVNFVGEGKA WYVASRNDAA 610 620 630 640 650 660 FQRDFFMNIA EELNLARALD TQFPYGVTAH RRTDGESEFI VVENYSNDSK SLVLPAVYRD 670 680 MVDQQPVQGS LTLAPWGSRV LTRYLE

References

[1]

"Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen." Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. J. Bacteriol. 188:4453-4463(2006) [PubMed: 16740952] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nepal516.

[2]

"Yersinia pestis Nepal516A whole genome shotgun sequencing project." Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S. Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nepal516 EMBL EEO75537.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000305 Genomic DNA. Translation: ABG19381.1. ACNQ01000017 Genomic DNA. Translation: EEO75537.1.
RefSeq	YP_648981.1. NC_008149.1.
3D structure databases
ProteinModelPortal	Q1CF49.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1CF49.
Protein family/group databases
CAZy	GH42. Glycoside Hydrolase Family 42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4125574.
GenomeReviews	Gene locus YPN_3054 in contig CP000305_GR.
KEGG	ypn:YPN_3054.
PATRIC	18605980. VBIYerPes46733_3629.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1874.
HOGENOM	HBG476453.
OMA	HGSDTVQ.
ProtClustDB	CLSK888649.
Enzyme and pathway databases
BioCyc	YPES377628:YPN_3054-MONOMER.
Family and domain databases
InterPro	IPR013739. Beta_galactosidase_C. IPR013738. Beta_galactosidase_Trimer. IPR003476. Glyco_hydro_42. IPR013529. Glyco_hydro_42_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K12308.
Pfam	PF02449. Glyco_hydro_42. 1 hit. PF08533. Glyco_hydro_42C. 1 hit. PF08532. Glyco_hydro_42M. 1 hit. [Graphical view]
PIRSF	PIRSF001084. B-galactosidase. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1CF49_YERPN

Accession

Primary (citable) accession number: Q1CF49

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)