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Protein
Submitted name:

Alpha-amylase protein

Gene

malS

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. alpha-glucan catabolic process Source: InterPro
  2. cellular oligosaccharide catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciYPES377628:GIXK-3825-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylase proteinImported (EC:3.2.1.1Imported)
Gene namesi
Name:malSImported
Ordered Locus Names:YPN_3724Imported
ORF Names:YP516_4234Imported
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)Imported
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008936 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. periplasmic space Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 PotentialImportedAdd
BLAST
Chaini20 – 687668 PotentialImportedPRO_5000115658Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi377628.YPN_3724.

Structurei

3D structure databases

ProteinModelPortaliQ1CD79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000273912.
KOiK01176.
OMAiFNWHNAT.
OrthoDBiEOG65QWH3.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR014635. A_amylase_MalS.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036917. Alph_amls_MalS. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1CD79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLTLPLLL VLSPAAMANW SLQHFPAFTE QDSGIFLSSS SLTKGEYPLK
60 70 80 90 100
FYQDKQCWQP TGPVKLNQML SLQPCQENIA IPWRLFRDGQ YQARIDTRSG
110 120 130 140 150
TPTLTLSVTA PVAEAVQVVT HVCQRWDGNP VTVDVSKTFA EGEIVRDFYS
160 170 180 190 200
GQTATVSLGK ITLRPAPESG GLLLLESAQT QQAAPFSWQN ATVYFALTDR
210 220 230 240 250
FNNGNPANDH SYGRHGDGMQ EIGTFHGGDL AGLTEKLDYL QQLGVNALWI
260 270 280 290 300
SSPLEQIHGW VGGGTKGDFP HYAYHGYYGL DWTRLDANMG TEQDLRTLVE
310 320 330 340 350
QAHKRGIRIL FDVVMNHVGY ATLADMQNDQ FGALYLQGDQ QEKTLGKRWS
360 370 380 390 400
DWTPGSGQTW HSFNDYINFS DKTAWDNWWG KKWIRTDIGD YDTPGYDDLT
410 420 430 440 450
MSLAFLPDIK TESTQPSGLP VFYRNKPDTA AQEIAGATPR DYMTHWLSQW
460 470 480 490 500
VRDYGIDGFR VDTAKHVEKP AWQQLKQQSI AALAEWKAAH PEQALDNLPF
510 520 530 540 550
WMTGEAWGHG VMKSDYYQNG FDAMINFDFQ DQANQALACF SSIESTYNQM
560 570 580 590 600
AEKLQNFNVL SYLSSHDTRL FFKDDAQQSL AKQQRAGSLL LLAPGAVQIF
610 620 630 640 650
YGDESGRKFG PTGSDPLQGT RSDMNWSELS GEKGALLAHW QKVSQFRARH
660 670 680
PAIGAGVQQS QQTANYYAFS RQHQGDKVLV VWVGDKN
Length:687
Mass (Da):77,102
Last modified:July 11, 2006 - v1
Checksum:iEF88234CF29F6036
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG20051.1.
ACNQ01000019 Genomic DNA. Translation: EEO74631.1.
RefSeqiYP_649651.1. NC_008149.1.

Genome annotation databases

EnsemblBacteriaiABG20051; ABG20051; YPN_3724.
EEO74631; EEO74631; YP516_4234.
GeneIDi4126141.
KEGGiypn:YPN_3724.
PATRICi18607557. VBIYerPes46733_4406.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG20051.1.
ACNQ01000019 Genomic DNA. Translation: EEO74631.1.
RefSeqiYP_649651.1. NC_008149.1.

3D structure databases

ProteinModelPortaliQ1CD79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi377628.YPN_3724.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG20051; ABG20051; YPN_3724.
EEO74631; EEO74631; YP516_4234.
GeneIDi4126141.
KEGGiypn:YPN_3724.
PATRICi18607557. VBIYerPes46733_4406.

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000273912.
KOiK01176.
OMAiFNWHNAT.
OrthoDBiEOG65QWH3.

Enzyme and pathway databases

BioCyciYPES377628:GIXK-3825-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR014635. A_amylase_MalS.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036917. Alph_amls_MalS. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
    Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
    J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Nepal516Imported.
  3. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
    Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516Imported.

Entry informationi

Entry nameiQ1CD79_YERPN
AccessioniPrimary (citable) accession number: Q1CD79
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: January 7, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.