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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:YPN_3828
ORF Names:YP516_4350
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000008936 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000202081 – 315Methionyl-tRNA formyltransferaseAdd BLAST315

Structurei

3D structure databases

ProteinModelPortaliQ1CCX5
SMRiQ1CCX5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni113 – 116Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
IPR001555 GART_AS
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373 GART, 1 hit

Sequencei

Sequence statusi: Complete.

Q1CCX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSLRIIFA GTPDFAARHL GALLSSQHKI VGVFTQPDRP AGRGNKLTPS
60 70 80 90 100
PVKILAEHHG IPVFQPKSLR PEENQHLVAD LNADIMVVVA YGLILPAAVL
110 120 130 140 150
AMPRLGCINV HGSLLPRWRG AAPIQRSVWA GDEKTGITIM QMDIGLDTGA
160 170 180 190 200
MLHKIECAIQ PEDTSATLYD KLAQLGPQGL LITLQQLAAG TALAEVQNET
210 220 230 240 250
QATYAEKLSK EEAKLDWTLS ATQLERCIRA FNPWPVSYFI VDEQPIKVWQ
260 270 280 290 300
AQVLPAGEDA EPGTIIHADK HGIQVATADG VLNITQLQPA GKKAMSAADL
310
LNSRREWFIP GSQLV
Length:315
Mass (Da):34,140
Last modified:July 11, 2006 - v1
Checksum:i24F167229DC2E0C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA Translation: ABG20155.1
ACNQ01000019 Genomic DNA Translation: EEO74742.1
RefSeqiWP_002209020.1, NZ_ACNQ01000019.1

Genome annotation databases

EnsemblBacteriaiABG20155; ABG20155; YPN_3828
EEO74742; EEO74742; YP516_4350
KEGGiypn:YPN_3828

Similar proteinsi

Entry informationi

Entry nameiFMT_YERPN
AccessioniPrimary (citable) accession number: Q1CCX5
Secondary accession number(s): D1Q2I9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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