Q1C932 (BETA_YERPA) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 42.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Choline dehydrogenase Short name=CDH Short name=CHD EC=1.1.99.1 | ||||
| Gene names |
| ||||
| Organism | Yersinia pestis bv. Antiqua (strain Antiqua) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 360102 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia |
Protein attributes
| Sequence length | 567 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750 |
| Catalytic activity | Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750 |
| Cofactor | FAD By similarity. HAMAP MF_00750 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750 |
| Sequence similarities | Belongs to the GMC oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro |
| Molecular function | choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 567 | 567 | Choline dehydrogenase HAMAP MF_00750 | PRO_0000258939 | |||||
Regions | |||||||||
| Nucleotide binding | 4 – 33 | 30 | FAD Potential | ||||||
Sites | |||||||||
| Active site | 473 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen." Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. J. Bacteriol. 188:4453-4463(2006) [PubMed: 16740952] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Antiqua. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000308 Genomic DNA. Translation: ABG13040.1. |
| RefSeq | YP_650985.1. NC_008150.1. |
3D structure databases | |
| ProteinModelPortal | Q1C932. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q1C932. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4121108. |
| GenomeReviews | Gene locus YPA_1073 in contig CP000308_GR. |
| KEGG | ypa:YPA_1073. |
| PATRIC | 18581284. VBIYerPes1796_1466. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG2303. |
| HOGENOM | HBG734713. |
| OMA | RSTAPYY. |
| ProtClustDB | PRK02106. |
Enzyme and pathway databases | |
| BioCyc | YPES360102:YPA_1073-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00750. Choline_dehydrogen. [Tree] |
| InterPro | IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view] |
| KO | K00108. |
| Pfam | PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000137. Alcohol_oxidase. 1 hit. |
| TIGRFAMs | TIGR01810. BetA. 1 hit. |
| PROSITE | PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETA_YERPA | ||||||||
| Accession | Primary (citable) accession number: Q1C932 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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