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Protein

Glucokinase

Gene

glk

Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPES360102:GHZU-2216-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:YPA_2166
OrganismiYersinia pestis bv. Antiqua (strain Antiqua)
Taxonomic identifieri360102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000001971 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323GlucokinasePRO_0000268794Add
BLAST

Proteomic databases

PRIDEiQ1C5Z1.

Interactioni

Protein-protein interaction databases

STRINGi360102.YPA_2166.

Structurei

3D structure databases

ProteinModelPortaliQ1C5Z1.
SMRiQ1C5Z1. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1C5Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS
60 70 80 90 100
EHQAKVTDAC IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND
110 120 130 140 150
FTAVSMAIPV LPAQDVLQFG GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR
160 170 180 190 200
WISLAGEGGH VDFAPNSEEE DQILAVLRQE LGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT
310 320
HPQPGLLGAG AYLRQKLGYE LSS
Length:323
Mass (Da):34,664
Last modified:July 10, 2006 - v1
Checksum:iA2465D600781CE37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000308 Genomic DNA. Translation: ABG14131.1.
RefSeqiYP_652076.1. NC_008150.1.

Genome annotation databases

EnsemblBacteriaiABG14131; ABG14131; YPA_2166.
GeneIDi4119049.
KEGGiypa:YPA_2166.
PATRICi18583822. VBIYerPes1796_2726.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000308 Genomic DNA. Translation: ABG14131.1.
RefSeqiYP_652076.1. NC_008150.1.

3D structure databases

ProteinModelPortaliQ1C5Z1.
SMRiQ1C5Z1. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi360102.YPA_2166.

Proteomic databases

PRIDEiQ1C5Z1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG14131; ABG14131; YPA_2166.
GeneIDi4119049.
KEGGiypa:YPA_2166.
PATRICi18583822. VBIYerPes1796_2726.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Enzyme and pathway databases

BioCyciYPES360102:GHZU-2216-MONOMER.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
    Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
    J. Bacteriol. 188:4453-4463(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Antiqua.

Entry informationi

Entry nameiGLK_YERPA
AccessioniPrimary (citable) accession number: Q1C5Z1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 11, 2006
Last sequence update: July 10, 2006
Last modified: January 6, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.