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Protein

Chitooligosaccharide deacetylase

Gene

chbG

Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.UniRule annotation

Catalytic activityi

N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate.UniRule annotation
Diacetylchitobiose-6-phosphate + H2O = N-monoacetylchitobiose-6-phosphate + acetate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: chitin degradation

This protein is involved in the pathway chitin degradation, which is part of Glycan degradation.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway chitin degradation and in Glycan degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Magnesium; via tele nitrogenUniRule annotation
Metal bindingi126 – 1261Magnesium; via pros nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciYPES360102:GHZU-2466-MONOMER.
UniPathwayiUPA00349.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitooligosaccharide deacetylaseUniRule annotation (EC:3.5.1.105UniRule annotation)
Short name:
CODUniRule annotation
Alternative name(s):
Chitin disaccharide deacetylaseUniRule annotation
Chitobiose deacetylaseUniRule annotation
Chitobiose-6P deacetylaseUniRule annotation
Chitotriose deacetylaseUniRule annotation
Chitotriose-6P deacetylaseUniRule annotation
Gene namesi
Name:chbGUniRule annotation
Ordered Locus Names:YPA_2411
OrganismiYersinia pestis bv. Antiqua (strain Antiqua)
Taxonomic identifieri360102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000001971 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 253253Chitooligosaccharide deacetylasePRO_1000067093Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1C596.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YdjC deacetylase family. ChbG subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000225034.
KOiK03478.
OMAiEPTHIDS.

Family and domain databases

CDDicd10803. YdjC_EF3048_like. 1 hit.
Gene3Di3.20.20.370. 1 hit.
HAMAPiMF_01246. COD. 1 hit.
InterProiIPR022948. COD_ChbG_bac.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
IPR006879. YdjC-like.
[Graphical view]
PfamiPF04794. YdjC. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1C596-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKLLIVNAD DFGLCKGQNY GIIDAFRNGV VSSTTAMMNS VDINHAAELS
60 70 80 90 100
AQYPALPVGM HFVLTFGRPL TAMPSLTDAN GELGKWLWQR AGAGTLDLNE
110 120 130 140 150
IAQELECQFE RFSAVFGRPP THIDSHHHVH MLPQIYPLVA AFAREKSLPL
160 170 180 190 200
RIDRHEVQQH GLTLDNPRSS EWFNAGFYGE NLSEPSFLQL LEHADQQGVN
210 220 230 240 250
SLEIMCHPAF IDQTLMTSGY CYPRLTELAI LTSPTLKPAI AQRGYRLGSF

LDC
Length:253
Mass (Da):28,171
Last modified:July 11, 2006 - v1
Checksum:iE249B90C5862D0C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000308 Genomic DNA. Translation: ABG14376.1.
RefSeqiWP_002212244.1. NZ_CP009906.1.

Genome annotation databases

EnsemblBacteriaiABG14376; ABG14376; YPA_2411.
KEGGiypa:YPA_2411.
PATRICi18584402. VBIYerPes1796_3012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000308 Genomic DNA. Translation: ABG14376.1.
RefSeqiWP_002212244.1. NZ_CP009906.1.

3D structure databases

ProteinModelPortaliQ1C596.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG14376; ABG14376; YPA_2411.
KEGGiypa:YPA_2411.
PATRICi18584402. VBIYerPes1796_3012.

Phylogenomic databases

HOGENOMiHOG000225034.
KOiK03478.
OMAiEPTHIDS.

Enzyme and pathway databases

UniPathwayiUPA00349.
BioCyciYPES360102:GHZU-2466-MONOMER.

Family and domain databases

CDDicd10803. YdjC_EF3048_like. 1 hit.
Gene3Di3.20.20.370. 1 hit.
HAMAPiMF_01246. COD. 1 hit.
InterProiIPR022948. COD_ChbG_bac.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. NODB_dom.
IPR006879. YdjC-like.
[Graphical view]
PfamiPF04794. YdjC. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCHBG_YERPA
AccessioniPrimary (citable) accession number: Q1C596
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 11, 2006
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.