Q1C0D5 (XYLG_YERPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylose import ATP-binding protein XylG
EC=3.6.3.17

Gene names

Name:	xylG
Ordered Locus Names:	YPA_4126

Organism

Yersinia pestis bv. Antiqua (strain Antiqua) [Complete proteome] [HAMAP]

Taxonomic identifier

360102 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia pestis

Protein attributes

Sequence length	510 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
Subunit structure	The complex is composed of two ATP-binding proteins (XylG), two transmembrane proteins (XylH) and a solute-binding protein (XylF) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. [View classification] Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW D-xylose-importing ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 510	510	Xylose import ATP-binding protein XylG		PRO_0000271519
Regions
	Domain	5 – 242	238	ABC transporter 1
	Domain	259 – 505	247	ABC transporter 2
	Nucleotide binding	37 – 44	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1C0D5 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 0CA4A44A426A27E0	FASTA	510	56,249
	10 20 30 40 50 60 MPYLLEMKDI TKQFGVVKAV DNISLTLEAG QVLSLCGENG SGKSTLMKVL CGIYPVGSYQ 70 80 90 100 110 120 GEIIFSGETL QAKNIRETEQ KGIAIIHQEL ALVKQMSVLE NMFLGSEWGR FGIMDYDAMY 130 140 150 160 170 180 LRCQRMLAQV KLVVDPHTPV SELGLGQQQL VEIAKALNKQ VRLLVLDEPT ASLTESETAI 190 200 210 220 230 240 LLDIIRDLRN HGIACIYISH KLNEVKEISD HICVIRDGRH IGTRPASTMS EDDIIAMMVG 250 260 270 280 290 300 RELKELYPHE AHHIGEEILR VENLCAWHPV NRHIRRVDDV SFSLKRGEIL GIAGLVGSGR 310 320 330 340 350 360 TETVQCLFGV YPGRWQGDIF IKGQAATIRT CQQAMKLGIA MVPEDRKKDG IVPVMGVGAN 370 380 390 400 410 420 ITLAALDDFT GAFSLLDDAK EQSIIVQSLA RLKVKTSSSE LAIARLSGGN QQKAILAKCL 430 440 450 460 470 480 LLNPQILILD EPTRGIDIGA KYEIYKLINQ LVQQGIAVIV ISSELPEVLG LSDRVLVMHQ 490 500 510 GRIKADLINH NLTQEKVMEA ALRSETHVTS

References

[1]

"Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen." Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Antiqua.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000308 Genomic DNA. Translation: ABG16087.1.
RefSeq	YP_654032.1. NC_008150.1.
3D structure databases
ProteinModelPortal	Q1C0D5.
ModBase	Search...
Protein-protein interaction databases
STRING	360102.YPA_4126.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABG16087; ABG16087; YPA_4126.
GeneID	4118356.
KEGG	ypa:YPA_4126.
PATRIC	18588387. VBIYerPes1796_4966.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1129.
KO	K10545.
OMA	GVMDYDA.
ProtClustDB	PRK13549.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR013455. ABC_transptr_xylose_ATP-bd. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
TIGRFAMs	TIGR02633. xylG. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. PS51280. XYLG. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLG_YERPA

Accession

Primary (citable) accession number: Q1C0D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	July 11, 2006
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program