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Protein

D-(-)-3-hydroxybutyrate oligomer hydrolase

Gene

Bcen_0357

Organism
Burkholderia cenocepacia (strain AU 1054)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D--3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.UniRule annotation

Catalytic activityi

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate.UniRule annotation

Pathwayi: butanoate metabolism

This protein is involved in the pathway butanoate metabolism, which is part of Lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway butanoate metabolism and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei309Charge relay systemUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

UniPathwayiUPA00863

Names & Taxonomyi

Protein namesi
Recommended name:
D-(-)-3-hydroxybutyrate oligomer hydrolaseUniRule annotation (EC:3.1.1.22UniRule annotation)
Short name:
3HB-oligomer hydrolaseUniRule annotation
Short name:
3HBOHUniRule annotation
Gene namesi
Ordered Locus Names:Bcen_0357
OrganismiBurkholderia cenocepacia (strain AU 1054)
Taxonomic identifieri331271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi

Subcellular locationi

  • Secreted UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_500012273627 – 696D-(-)-3-hydroxybutyrate oligomer hydrolaseAdd BLAST670

Proteomic databases

PRIDEiQ1BYN6

Family & Domainsi

Sequence similaritiesi

Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000263490
KOiK07518
OMAiNPEKDWG

Family and domain databases

HAMAPiMF_01906 3HBOH, 1 hit
InterProiView protein in InterPro
IPR016582 OHBut_olig_hydro_put
PfamiView protein in Pfam
PF10605 3HBOH, 1 hit
PIRSFiPIRSF011409 HObutyrate_olig_hydrol, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1BYN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKLGWGRRV VWGAALAAVA MLGACNGDES AERNRLPGFV SGSVRTTAYD
60 70 80 90 100
GASDDLLTAG LGKTGLAAAT APGFANPSRP TSAELRRLAI WSNYRALVDM
110 120 130 140 150
SANGGYGRFW GPNVDLDGND TLGEGKIPGT EYLAYADDGS GSKNVTLLVQ
160 170 180 190 200
VPASFNPAQP CIVTATSSGS RGVYGAISAA GEWALKRGCA VAYNDKGGGN
210 220 230 240 250
GAHELGSDTV TLIDGTLANA VLAGTASLFT ANVTSGDLAA FNSRFPNRYA
260 270 280 290 300
FKHAHSQQNP EQDWGRVTLQ SVEFAYWALN EQFGPVIDGA RHGVRYRAGD
310 320 330 340 350
ITTIAASVSN GGGASLAAAE QDNRGWITAV VVGEPQINVR MAPNAVVRAG
360 370 380 390 400
GQPVPSFGRP LADYATLANL LEPCAAASAS LAGAPYLSAL PATTTQSIRT
410 420 430 440 450
QRCATLAAAG LVAGADTQSQ AADALAQLHA AGYLADSDLL QAPMWDSQAI
460 470 480 490 500
PAIAVTYANA YTRSRVTDNL CNFSFATTNP ATGVVAAPAA SPMPSVFGVG
510 520 530 540 550
NGVPPTAGIN LVFNDGAGTD HRLATPDASF AGALCLRQLW TNGMLGMPAN
560 570 580 590 600
VDAVRVNANL HGKPAIIVQG RSDALVPVNH ASRAYVAQNG ISEAGRSQLV
610 620 630 640 650
FYEVTNGQHF DAFLSVPGFD TRFVPVHYYN VQALNLMWRH LKNGAPLPPS
660 670 680 690
QVIRTVPRGG TPGAAPALTS ANLPPISTAP GANAIATGVG TIDVPL
Length:696
Mass (Da):71,693
Last modified:July 11, 2006 - v1
Checksum:i9C7DCC29A2FC4146
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000378 Genomic DNA Translation: ABF75269.1
RefSeqiWP_011544713.1, NC_008060.1

Genome annotation databases

EnsemblBacteriaiABF75269; ABF75269; Bcen_0357
KEGGibcn:Bcen_0357

Similar proteinsi

Entry informationi

Entry nameiHBOH_BURCA
AccessioniPrimary (citable) accession number: Q1BYN6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: May 23, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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