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Q1BYF5 (UPPP1_BURCA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1
EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Ordered Locus Names:Bcen_0438
OrganismBurkholderia cenocepacia (strain AU 1054) [Complete proteome] [HAMAP]
Taxonomic identifier331271 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP MF_01006

Catalytic activity

Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase 1 HAMAP MF_01006
PRO_0000250226

Regions

Transmembrane83 – 10321Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane187 – 20721Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane252 – 27221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q1BYF5 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 2E18CE6F2C99B5EF

FASTA27630,227
        10         20         30         40         50         60 
MDWILICKAL ILGVVEGLTE FLPVSSTGHL IVAGSFLNFN DSHAKTFDVV IQFGAILAVC 

        70         80         90        100        110        120 
WEYRQRIVSV VSGLPSRPDA QRFTLNVVIA TIPAIALGLL FEKKIKAVLF SPVPVAFALV 

       130        140        150        160        170        180 
VGGAIILWAE ARQRERSEPP RVMSVDALTP LDALKVGIAQ CFALVPGMSR SGSTIIGGML 

       190        200        210        220        230        240 
FGLDRRVATE FSFFLAIPII FGATLYETVK DWQAFTVDSL GLFALGLVAA FVSAFVCVRW 

       250        260        270 
LLRYVATHDF TVFAWYRIAF GLFVLLVGYS GWLNWA

« Hide

References

[1]"Complete sequence of chromosome 1 of Burkholderia cenocepacia AU 1054."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AU 1054.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000378 Genomic DNA. Translation: ABF75350.1.
RefSeqYP_620323.1. NC_008060.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ1BYF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4090930.
GenomeReviewsGene locus Bcen_0438 in contig CP000378_GR.
KEGGbcn:Bcen_0438.
PATRIC19044341. VBIBurCen11237_0452.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHBG391969.
OMAIAFMPAV.
PhylomeDBQ1BYF5.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycBCEN331271:BCEN_0438-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
[Tree]
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
KOK06153.
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. Undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP1_BURCA
AccessionPrimary (citable) accession number: Q1BYF5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: July 11, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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