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Protein

Guanylate kinase

Gene

gmk

Organism
Burkholderia cenocepacia (strain AU 1054)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi28 – 35ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCEN331271:G1G6K-542-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Bcen_0520
OrganismiBurkholderia cenocepacia (strain AU 1054)
Taxonomic identifieri331271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002400 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002662951 – 227Guanylate kinaseAdd BLAST227

Structurei

3D structure databases

ProteinModelPortaliQ1BY73
SMRiQ1BY73
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 199Guanylate kinase-likeUniRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1BY73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSTRDGHA SHSLHGGVYP GNLFMVVAPS GAGKSTLVNA LLSKDSDICL
60 70 80 90 100
SISYTTRKPR PGEQDGQHYH FTTVEDFRAR HAAHEFLESA EVHGNYYGTS
110 120 130 140 150
RVWIEEQMRN GHDVLLEIDW QGALQVKKQF RNAVGIFILP PSLDALEERL
160 170 180 190 200
KKRGQDEPNV ITRRLLAAGS EIAHASEAEY VVINENFERA LAELECIVAA
210 220
TRLRFASQYA RHTELFIDLG VHLPHAE
Length:227
Mass (Da):25,386
Last modified:July 11, 2006 - v1
Checksum:i4F9344BC814FA4C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000378 Genomic DNA Translation: ABF75432.1
RefSeqiWP_011544849.1, NC_008060.1

Genome annotation databases

EnsemblBacteriaiABF75432; ABF75432; Bcen_0520
KEGGibcn:Bcen_0520

Similar proteinsi

Entry informationi

Entry nameiKGUA_BURCA
AccessioniPrimary (citable) accession number: Q1BY73
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 11, 2006
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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