Q1BY27 (KCY_BURCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	Bcen_0567

Organism

Burkholderia cenocepacia (strain AU 1054) [Complete proteome] [HAMAP]

Taxonomic identifier

331271 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Cytidylate kinase HAMAP MF_00238		PRO_1000048193
Regions
	Nucleotide binding	17 – 25	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1BY27 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 532E91F3B0B6BE10	FASTA	228	24,381
	10 20 30 40 50 60 MKSTRPFHPT PVITIDGPTA SGKGTVAALV AAHLGFHLLD SGALYRLAAL ASVRYGIAAE 70 80 90 100 110 120 DIDALVKLID DLHITFREGC AQLDGVDVSN DIRAEAVGNR ASAIAVHGPV RTALVARQRA 130 140 150 160 170 180 FRKTPGLVAD GRDMGTVIFP DAVLKVFLTA SAEARATRRH KQLMQKGFSA NIDDLLRDLR 190 200 210 220 ERDARDSNRA AAPLKPAADA KLLDTSALSV DEAVDQVLQW YRALGQPA

References

[1]

"Complete sequence of chromosome 1 of Burkholderia cenocepacia AU 1054." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AU 1054.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000378 Genomic DNA. Translation: ABF75478.1.
RefSeq	YP_620451.1. NC_008060.1.
3D structure databases
ProteinModelPortal	Q1BY27.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1BY27.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4093798.
GenomeReviews	Gene locus Bcen_0567 in contig CP000378_GR.
KEGG	bcn:Bcen_0567.
PATRIC	19044607. VBIBurCen11237_0577.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0283.
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	Q1BY27.
ProtClustDB	PRK00023.
Enzyme and pathway databases
BioCyc	BCEN331271:BCEN_0567-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BURCA

Accession

Primary (citable) accession number: Q1BY27

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 11, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program