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Protein

UvrABC system protein C

Gene

uvrC

Organism
Burkholderia cenocepacia (strain AU 1054)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Bcen_0663
OrganismiBurkholderia cenocepacia (strain AU 1054)
Taxonomic identifieri331271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002400 Componenti: Chromosome 1

Subcellular locationi

Q1BXT2:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002648761 – 681UvrABC system protein CAdd BLAST681

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1BXT2.
SMRiQ1BXT2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 100GIY-YIGUniRule annotationAdd BLAST79
Domaini209 – 244UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279961.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1BXT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPEASATP FEPKKILAQL PHMPGVYRYY DTTGAVLYVG KARDLKKRVS
60 70 80 90 100
SYFTKTQLSP RIAMMVTRIA RIETTVTRSE AEALLLENNL IKALAPRYNI
110 120 130 140 150
LFRDDKSYPY LKLTAHRFPR MAYYRGSVDK QNQYFGPFPS AWAVRESIQI
160 170 180 190 200
LQRVFQLRTC EDSVFNNRTR PCLLHQIGRC TAPCVGAISE EDYAVDVSNA
210 220 230 240 250
ARFLLGRQSE VMKELEQKMH AFAAELKFEQ AAAVRNQMSS LATVLHQQAI
260 270 280 290 300
EVGSDSDVDI LAVVAQGGRV CVNLAMVRGG RHLGDKAYFP THVESALTLA
310 320 330 340 350
EGGLGEEVEP AEAVDATADA PVDTVPDQPA EEAGSARGAA AASVEAEVLD
360 370 380 390 400
AFIAQHYLGN RVPPVLVVSH APASRDLLEL LSEQAGHKVS LVRQPQGQRR
410 420 430 440 450
AWLSMAEQNA RLALARLLSE QGSQQARTRA LADTLSYDSD DLATLRIECF
460 470 480 490 500
DISHTMGEAT QASCVVYHHH KMQSSEYRRY NITGITPGDD YAAMRQVLTR
510 520 530 540 550
RYEKMVEQAA QAAAVDEAAG IDGESTRQAE ASSLLPNIVL IDGGKGQVEI
560 570 580 590 600
ARQVFTELGL DTSMLVGVAK GEGRKVGLET LVFADGRAPL ELGKESAALM
610 620 630 640 650
LVAQIRDEAH RFAITGMRAK RAKARQTSRL EELEGVGAKR RQRLLARFGG
660 670 680
LRGVVAASVE ELASVEGISH ALAEQIYKQL H
Length:681
Mass (Da):74,629
Last modified:July 11, 2006 - v1
Checksum:i851559A03AFE22FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000378 Genomic DNA. Translation: ABF75573.1.
RefSeqiWP_011544950.1. NC_008060.1.

Genome annotation databases

EnsemblBacteriaiABF75573; ABF75573; Bcen_0663.
KEGGibcn:Bcen_0663.

Similar proteinsi

Entry informationi

Entry nameiUVRC_BURCA
AccessioniPrimary (citable) accession number: Q1BXT2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 11, 2006
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families