Reviewed, UniProtKB/Swiss-Prot Q1BKI8 (MQO_BURCA)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	Bcen_4992

Organism

Burkholderia cenocepacia (strain AU 1054) [Complete proteome] [HAMAP]

Taxonomic identifier

331271 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	553 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 553	553	Probable malate:quinone oxidoreductase		PRO_0000325489

Sequences

	Sequence		Length	Mass (Da)
	Q1BKI8-1 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 113DCA21FC45E048	FASTA	553	60,584
	10 20 30 40 50 60 MKKGSAVIKT LRVILSALAL CVATSSAHAA DTKKVDVLLV GGGIMSSTLG VWLHELQPNW 70 80 90 100 110 120 SMTMVERLDG VALESSNGWN NAGTGHSALA ELNYTPEKAD GKVDISKAIE INESFQISRQ 130 140 150 160 170 180 FWAWQVKQGV LKNPHSFINS TPHMSFVWGD DNVRFLKKRY EALQASPLFR GMQYSEDYDQ 190 200 210 220 230 240 IKQWVPLMME GRDRNQKVAA TWTPIGTDVN FGEITRQFVG YLKTQPNFTL SLSSEVREIT 250 260 270 280 290 300 RNADGTWHVS WVKLHSDEPP QSVDAKFVFI GAGGGALHLL QASGIPEAKD YGAFPVGGSF 310 320 330 340 350 360 LVTDNPEVVK QHLAKAYGKA SVGSPPMSVP HLDTRIIDGK KIILFGPFAT FSTKFLKNGS 370 380 390 400 410 420 YFDLAKSTNL HNVAPMMRVG VDEFPLVQYL AGQLMLTDDD RFNALKEYFP NAKKEDWRLW 430 440 450 460 470 480 QAGQRVQIIK RDPVKGGVLK LGTEIVASQD GSIAGLLGAS PGASTAAPIM LNLMQKVFKD 490 500 510 520 530 540 KVATPEWQQK IRQIVPSYGT KLNDSPAKVV EEWTYTSDVL QLSPPPKIDL GAPSQATGNA 550 PARPAKASAD MAL

References

[1]

"Complete sequence of chromosome 2 of Burkholderia cenocepacia AU 1054." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000379 Genomic DNA. Translation: ABF79867.1.
RefSeq	YP_624840.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4094148.
GenomeReviews	Gene locus Bcen_4992 in contig CP000379_GR.
KEGG	bcn:Bcen_4992.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1BKI8.
Enzyme and pathway databases
BioCyc	BCEN331271:BCEN_4992-MON.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BURCA

Accession

Primary (citable) accession number: Q1BKI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	July 11, 2006
Last modified:	November 4, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)