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Protein

NAD(P)H dehydrogenase (quinone)

Gene

Bcen_5766

Organism
Burkholderia cenocepacia (strain AU 1054)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12NAD(P)UniRule annotation1
Binding sitei99SubstrateUniRule annotation1
Binding sitei135FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15FMNUniRule annotation6
Nucleotide bindingi79 – 81FMNUniRule annotation3
Nucleotide bindingi114 – 120FMNUniRule annotation7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCEN331271:G1G6K-5998-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Bcen_5766
OrganismiBurkholderia cenocepacia (strain AU 1054)
Taxonomic identifieri331271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002400 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002910081 – 200NAD(P)H dehydrogenase (quinone)Add BLAST200

Structurei

3D structure databases

ProteinModelPortaliQ1BIC1
SMRiQ1BIC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 191Flavodoxin-likeUniRule annotationAdd BLAST188

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000030539
KOiK03809
OMAiVGVPYAC

Family and domain databases

Gene3Di3.40.50.3601 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q1BIC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVLVLYYS SYGHIETMAQ HIVEGAKSVP GVEVTLKRVP ETIPVDQARA
60 70 80 90 100
IGVKVDQAAP VATVDELADY DAIIFGTPTR FGNMAGQMRT FLDQTGGLWM
110 120 130 140 150
KGALVGKIGS VFASTGTQHG GQETTITSFH TTLLHHGMVI VGVPYACSGL
160 170 180 190 200
VNMSEITGGT PYGATTLAGA DGSRQPSANE LDIARYQGKH VAELASKLAS
Length:200
Mass (Da):20,993
Last modified:July 11, 2006 - v1
Checksum:iE21375E7658368DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000380 Genomic DNA Translation: ABF80634.1
RefSeqiWP_011549309.1, NC_008062.1

Genome annotation databases

EnsemblBacteriaiABF80634; ABF80634; Bcen_5766
KEGGibcn:Bcen_5766

Similar proteinsi

Entry informationi

Entry nameiNQOR_BURCA
AccessioniPrimary (citable) accession number: Q1BIC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: July 11, 2006
Last modified: February 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome