Q1BHI4 (GLND_BURCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Bcen_6056

Organism

Burkholderia cenocepacia (strain AU 1054) [Complete proteome] [HAMAP]

Taxonomic identifier

331271 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex › Burkholderia cenocepacia

Protein attributes

Sequence length	858 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 858	858	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000022330

Sequences

	Sequence		Length	Mass (Da)
	Q1BHI4 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 407190972C69EE1E	FASTA	858	96,896
	10 20 30 40 50 60 MSAHAAPSPE ALSRRAEFKA AKTEMLERFR HAANVASLMH ALSKLTDDAL KRVWDECGLP 70 80 90 100 110 120 ATLALVAVGG YGRGELAPYS DVDILVLLPD AHDAALDARI ERFIGMAWDL GLEIGSSVRT 130 140 150 160 170 180 VAQCIEEASQ DVTVQTSLLE ARRIVGSTAL FERFTVRYHE ALDARAFFTA KVLEMRQRHA 190 200 210 220 230 240 KFQDTPYSLE PNVKESPGGL RDLQTILWIA RAAGFGSSWR ELDTRGLITD REARELRRNE 250 260 270 280 290 300 GFLKTLRARL HVIAGRRQDM LVFDLQTQAA ESFGYQPTQA KRASEQLMRR YYWAAKAVTQ 310 320 330 340 350 360 LATILIQNIE AQLFPATSGI TRVLSADRFV EKQGMLEIVD DGVFERHPDA ILEAFLLYET 370 380 390 400 410 420 TRGVKGLSAR TLRALYNSRE IMNNAWRRDP QNRATFMRIL QQPEGITHAF RLMNQTSVLG 430 440 450 460 470 480 RYLLNFRRIV GQMQHDLYHV YTVDQHILMV LRNIRRFAVA EHAHEYPFCS QLIGNFERPW 490 500 510 520 530 540 VLYVAALFHD IAKGRGGDHS TLGMADARRF CREHGIAGDD AALIVWLVQH HLTMSQVAQK 550 560 570 580 590 600 QDTSDPEVIK RFAEVVGNER YLTALYLLTV ADIRGTSPKV WNTWKGKLLE DLYRITLAVL 610 620 630 640 650 660 GGANPDAHSE LKSRQEQALA LLRLETVPDD AHRALWDQLD VGFFLRHDAA DIAWQTRVLY 670 680 690 700 710 720 RHVNAETAIV RARPSPIGDA LQVLVYVKDR PDLFAGICAY FDRNGLSVLD ARVSTTRHGY 730 740 750 760 770 780 ALDNFIVTQT ERDVRYRDIA NLVEQQLATR LAETASLPEP SKGRLSRLSR TFPITPRVDL 790 800 810 820 830 840 RADERGQYYI LSVSANDRPG LLYSIARVLA EHRIGVHAAR INTLGERVED IFLLAGAGLS 850 DNRLQIQLET ELLRAIAV

References

[1]

"Complete sequence of chromosome 3 of Burkholderia cenocepacia AU 1054." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K., Tiedje J.M., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AU 1054.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000380 Genomic DNA. Translation: ABF80921.1.
RefSeq	YP_625894.1. NC_008062.1.
3D structure databases
ProteinModelPortal	Q1BHI4.
ModBase	Search...
Protein-protein interaction databases
STRING	331271.Bcen_6056.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABF80921; ABF80921; Bcen_6056.
GeneID	4097107.
KEGG	bcn:Bcen_6056.
PATRIC	19056150. VBIBurCen11237_6260.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK03059.
Enzyme and pathway databases
BioCyc	BCEN331271:GHKX-596-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_BURCA

Accession

Primary (citable) accession number: Q1BHI4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 11, 2006
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program