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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Burkholderia cenocepacia (strain AU 1054)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-1,6-bisphosphate aldolase (Bcen_2015)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei350Proton donorUniRule annotation1
Active sitei381UniRule annotation1
Active sitei503UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBCEN331271:G1G6K-6429-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Bcen_6162
OrganismiBurkholderia cenocepacia (strain AU 1054)
Taxonomic identifieri331271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002400 Componenti: Chromosome 3

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526111 – 540Glucose-6-phosphate isomeraseAdd BLAST540

Structurei

3D structure databases

ProteinModelPortaliQ1BH79
SMRiQ1BH79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000261370
KOiK01810
OMAiVERCKAM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q1BH79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLKSLPAWT ALQSHFEQIR HARLRDWFAP ENDRAPTRAE RFTIPGGGLA
60 70 80 90 100
ADFSKNRIDD ETLRLLVQLA RDAGVEARRD AMFAGEIVNP TEGRAALHTA
110 120 130 140 150
LRATDPQAPF HAQVSAERAK MATFARAVRS GTWTGYTGKR IRHVINIGIG
160 170 180 190 200
GSDLGPKMVV HALHHVATPE ISTHFVSNVD GADLARVLEQ VDPEETLAII
210 220 230 240 250
VSKTFTTLET MTNARSLRDW FVARGCPEDA LAKHFVGVSA NPAEVVKFGI
260 270 280 290 300
AADNVFEMWD WVGGRYSLWS AVGLSIMIAI GPEQFDELLA GANDMDRHFR
310 320 330 340 350
EAPLERNLPV LLGLIGIWYR NFFGSQSYLV APYSEALHYL PSYLQQLEME
360 370 380 390 400
SNGKSARLDG TFVDYPTSAV TWGEPGTNGQ HAFFQMLHQG PTIVPIDFIA
410 420 430 440 450
VLTPEHPLAG HHPKLLANCF AQSEALMLGR TLEEARKVAG PGKEALAPHL
460 470 480 490 500
TFPGNRPTTT LLVDALTPRT LGALIALYEH KVLVQATVWD INPFDQWGVE
510 520 530 540
LGKILGKVVE GDLSAESVDP AKHDSSTTAL IERARAALKR
Length:540
Mass (Da):59,259
Last modified:October 17, 2006 - v2
Checksum:i22EB0E18DDD52882
GO

Sequence cautioni

The sequence ABF81026 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000380 Genomic DNA Translation: ABF81026.1 Different initiation.
RefSeqiWP_041489543.1, NC_008062.1

Genome annotation databases

EnsemblBacteriaiABF81026; ABF81026; Bcen_6162
KEGGibcn:Bcen_6162

Similar proteinsi

Entry informationi

Entry nameiG6PI_BURCA
AccessioniPrimary (citable) accession number: Q1BH79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: March 28, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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