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Q1BH71 (MSRB_BURCA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrB

EC=1.8.4.12
Alternative name(s):
Peptide-methionine (R)-S-oxide reductase
Gene names
Name:msrB
Ordered Locus Names:Bcen_6170
OrganismBurkholderia cenocepacia (strain AU 1054) [Complete proteome] [HAMAP]
Taxonomic identifier331271 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length143 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400

Cofactor

Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.

Sequence similarities

Belongs to the MsrB Met sulfoxide reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 143143Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
PRO_1000145351

Sites

Active site1281Nucleophile By similarity
Metal binding551Zinc By similarity
Metal binding581Zinc By similarity
Metal binding1041Zinc By similarity
Metal binding1071Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1BH71 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 838E9BC10B0CD2AF

FASTA14316,193
        10         20         30         40         50         60 
MSHDSDDKTF PYQKDDAELR RRLTPMQYEV TQHAATERAF TGEYTDTEDA GIYKCVVCST 

        70         80         90        100        110        120 
PLFESGAKFH SGCGWPSYFK PLNGEVIDEK VDYSHGMVRV EVRCNNCGAH LGHVFEDGPR 

       130        140 
DKTGLRYCIN SAALNFESRP ENE 

« Hide

References

[1]"Complete sequence of chromosome 3 of Burkholderia cenocepacia AU 1054."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AU 1054.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000380 Genomic DNA. Translation: ABF81034.1.
RefSeqYP_626007.1. NC_008062.1.

3D structure databases

ProteinModelPortalQ1BH71.
SMRQ1BH71. Positions 10-140.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1BH71.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4096524.
GenomeReviewsGene locus Bcen_6170 in contig CP000380_GR.
KEGGbcn:Bcen_6170.
PATRIC19056402. VBIBurCen11237_6383.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0229.
HOGENOMHBG715255.
OMAFTDGPVD.
PhylomeDBQ1BH71.
ProtClustDBCLSK930638.

Enzyme and pathway databases

BioCycBCEN331271:BCEN_6170-MONOMER.

Family and domain databases

HAMAPMF_01400. MsrB.
[Tree]
InterProIPR002579. Methionine_sulphoxide_MsrB.
IPR011057. Mss4-like.
[Graphical view]
Gene3DG3DSA:2.170.150.20. MsrB. 1 hit.
KOK07305.
PfamPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMSSF51316. Mss4_like. 1 hit.
TIGRFAMsTIGR00357. TIGR00357. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_BURCA
AccessionPrimary (citable) accession number: Q1BH71
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 11, 2006
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families