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Protein
Submitted name:

PAS/PAC sensor hybrid histidine kinase

Gene

Mmcs_0350

Organism
Mycobacterium sp. (strain MCS)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphorelay sensor kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciMSP164756:GHQ8-353-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PAS/PAC sensor hybrid histidine kinaseImported (EC:2.7.13.3Imported)
Gene namesi
Ordered Locus Names:Mmcs_0350Imported
OrganismiMycobacterium sp. (strain MCS)Imported
Taxonomic identifieri164756 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000001972 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 PotentialImportedAdd
BLAST
Chaini22 – 13901369 PotentialImportedPRO_5000123970Add
BLAST

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi164756.Mmcs_0350.

Structurei

3D structure databases

ProteinModelPortaliQ1BF63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG0745.
HOGENOMiHOG000217841.
KOiK00936.
OMAiGMWEKVV.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR013656. PAS_4.
IPR001932. PP2C-like_dom.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF13581. HATPase_c_2. 1 hit.
PF00512. HisKA. 1 hit.
PF08448. PAS_4. 1 hit.
PF13426. PAS_9. 1 hit.
PF00072. Response_reg. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00086. PAC. 2 hits.
SM00091. PAS. 1 hit.
SM00331. PP2C_SIG. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 2 hits.
SSF55874. SSF55874. 2 hits.
SSF81606. SSF81606. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50113. PAC. 1 hit.
PS50112. PAS. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1BF63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVEEAGAAS LTSSASALFG ADPEVGRHLA MVDWASTALG DPTAWPQSLR
60 70 80 90 100
TAVNILLSSR FPMWMAWGPE LTFFCNAAYR RDTLGRKYPW ALGRPASEVW
110 120 130 140 150
AEIWPDIGPR IESVLSTGRA TWDSALLLFL ERSGYSEETY HTFSYSPLRD
160 170 180 190 200
DGGQVVGMLC VVSEDTERVI AERRMTTLRD LGSDPSVVRT ERQMLDFAAE
210 220 230 240 250
QLGRNRHDLP FTLTYLFGDD GDAVLAASSG ITPGHAAAPE TLSADGMSVW
260 270 280 290 300
PVRQPAEGET VLLEIDGESL ALPRGVWPDP PTQALVVPLL QQGADPVGFL
310 320 330 340 350
VAALNSHRRL DAPYRGFIEL VAGHIAAGIG SARSYGAQQR RAEELAELDL
360 370 380 390 400
AKTTFFSNIS HEFRTPLTLI LGPLAEMLRT SELDVRVREE LELAHRNGLR
410 420 430 440 450
LAKLVNTLLD FSRIQAGRMR AQFEPVDLAA VTAELASVFR SAIERAGLEF
460 470 480 490 500
TVDCPPLAEP VFVDRDMWEK VVLNLLSNAL KFTREGAVTV RVTADDGVAV
510 520 530 540 550
VTVADTGVGI PEAEMPRLFE RFHRVETVDA RSTEGSGIGL ALVKELIGLH
560 570 580 590 600
GGTIGAQSEE GRGTTFTIQM PFGAAHLPAD EVVPHGRVSG VSANADPYLQ
610 620 630 640 650
EALRWLPASD PESDSRDPIA APVPATGGSG TGTAVPARIL IADDNADMRA
660 670 680 690 700
YLTGLLRGAG YEVTAVSDGR QALESIRAEL PDLVVSDVMM PGLDGLELVA
710 720 730 740 750
ALRAESRTAA LPVLLLSARA GQESSIEGLH AGADDYLVKP FAAAELLARV
760 770 780 790 800
HANVALARLR NHHSRWRTAL IDSLQEAFFV CDEDGAVVEI NAAFSQILGY
810 820 830 840 850
GPEGLPYQPV QPWWPDPDTD PEGYRQTSQA FGGVMGQSRG EFTFPVVHRD
860 870 880 890 900
GHRLWVNANF NPARDPDTGR RVAVGTFRDV TAEHYIVQRE MALAALNAQL
910 920 930 940 950
AEADTLDGAL RAAVAELHRL WQARRVLAVT FPGADGDVTP DVICAGEAVQ
960 970 980 990 1000
WSDLPAGQRD TITALRTADL LTADTEEYGT AGITLQHPRG VLVLWIELLE
1010 1020 1030 1040 1050
QRPFTPEDRT LLTVLAGRLG QGLQRVHRLD QQRETALTLQ HAILGPARLP
1060 1070 1080 1090 1100
GGFAVRYHPA TRPLQVGGDW YDVVDLDGDC IALVVGDCVG HDLEAATVMG
1110 1120 1130 1140 1150
QLRSACRALL LDQPSPGAAL AGLDRFAARL PGARCTTVWC AVLSPETGEL
1160 1170 1180 1190 1200
VYSSAGHPPP ILVGPDDGHR VLDDARGFAL ALRPDQERPE ARVTLSARTT
1210 1220 1230 1240 1250
LLLYTDGLVE RRRASLETGI GRAADLVADG RSDALDAVAD QLMSRLAPDG
1260 1270 1280 1290 1300
GYQDDVALLL YRQPAPLDLV FPARNEYLAS SRTALRRWLT KAGVGPDQAM
1310 1320 1330 1340 1350
NVLIAAGEAV ANAIEHGHRD RPDGRVTLRA TAMVDRLQVS ILDTGSWKTP
1360 1370 1380 1390
RTEVDTRRGR GVALMEGLMD DVTIRPGDDG TTVHLEAGIL
Length:1,390
Mass (Da):149,987
Last modified:July 11, 2006 - v1
Checksum:iC7A544F5A6D84FCB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000384 Genomic DNA. Translation: ABG06471.1.
RefSeqiYP_637527.1. NC_008146.1.

Genome annotation databases

EnsemblBacteriaiABG06471; ABG06471; Mmcs_0350.
KEGGimmc:Mmcs_0350.
PATRICi18110795. VBIMycSp106721_0361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000384 Genomic DNA. Translation: ABG06471.1.
RefSeqiYP_637527.1. NC_008146.1.

3D structure databases

ProteinModelPortaliQ1BF63.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi164756.Mmcs_0350.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG06471; ABG06471; Mmcs_0350.
KEGGimmc:Mmcs_0350.
PATRICi18110795. VBIMycSp106721_0361.

Phylogenomic databases

eggNOGiCOG0745.
HOGENOMiHOG000217841.
KOiK00936.
OMAiGMWEKVV.
OrthoDBiEOG6G4VQG.

Enzyme and pathway databases

BioCyciMSP164756:GHQ8-353-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 2 hits.
InterProiIPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR013656. PAS_4.
IPR001932. PP2C-like_dom.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF13581. HATPase_c_2. 1 hit.
PF00512. HisKA. 1 hit.
PF08448. PAS_4. 1 hit.
PF13426. PAS_9. 1 hit.
PF00072. Response_reg. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00086. PAC. 2 hits.
SM00091. PAS. 1 hit.
SM00331. PP2C_SIG. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 2 hits.
SSF55874. SSF55874. 2 hits.
SSF81606. SSF81606. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50113. PAC. 1 hit.
PS50112. PAS. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MCSImported.

Entry informationi

Entry nameiQ1BF63_MYCSS
AccessioniPrimary (citable) accession number: Q1BF63
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: April 1, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.