Q1B9Y5 (Q1B9Y5_MYCSS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase EMBL ABG08299.1
EC=3.6.1.23 EMBL ABG08299.1

Gene names

Ordered Locus Names:

Mmcs_2191

Organism

Mycobacterium sp. (strain MCS) [Complete proteome] [HAMAP]

Taxonomic identifier

164756 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA By similarity. SAAS SAAS008181
Catalytic activity	dUTP + H2O = dUMP + diphosphate. SAAS SAAS008181
Cofactor	Magnesium By similarity. SAAS SAAS008181

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS008181
Ligand	Magnesium SAAS SAAS008181 Metal-binding SAAS SAAS008181
Molecular function	Hydrolase SAAS SAAS008181 EMBL ABG08299.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dUTP diphosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1B9Y5 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 96C4D6ECC532B0E2	FASTA	139	14,406
	10 20 30 40 50 60 MPARAHDGDA GVDLFSARDV ELAPGQRELV PTGIAVAIPH GMVGLVHPRS GLAARVGLSI 70 80 90 100 110 120 VNSPGTIDAG YRGEIKVSLI NLDPHAPIVI RRGDRIAQLL VQRVELPELV EVTSFDEAGL 130 AETTRGEGGH GSSGGHASL

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. MCS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MCS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000384 Genomic DNA. Translation: ABG08299.1.
RefSeq	YP_639355.1. NC_008146.1.
3D structure databases
ProteinModelPortal	Q1B9Y5.
SMR	Q1B9Y5. Positions 1-129.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1B9Y5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000061139; EBMYCP00000059306; EBMYCG00000061134.
GeneID	4111024.
GenomeReviews	Gene locus Mmcs_2191 in contig CP000384_GR.
KEGG	mmc:Mmcs_2191.
PATRIC	18114580. VBIMycSp106721_2243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0756.
GeneTree	EBGT00050000017683.
HOGENOM	HBG436079.
OMA	KIAQMVI.
ProtClustDB	PRK00601.
Family and domain databases
InterPro	IPR008180. dUTP_pyroPase. IPR008181. dUTP_pyroPase_sf. [Graphical view]
KO	K01520.
PANTHER	PTHR11241. PTHR11241. 1 hit.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00576. Dut. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1B9Y5_MYCSS

Accession

Primary (citable) accession number: Q1B9Y5

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)