Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q1B6W3 (RSMH_MYCSS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase H
EC=2.1.1.199
Alternative name(s):
16S rRNA m(4)C1402 methyltransferase
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Gene names
Name:rsmH
Synonyms:mraW
Ordered Locus Names:Mmcs_3264
OrganismMycobacterium sp. (strain MCS) [Complete proteome] [HAMAP]
Taxonomic identifier164756 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA By similarity. HAMAP MF_01007

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA. HAMAP MF_01007

Subcellular location

Cytoplasm By similarity HAMAP MF_01007.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmH family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 324324Ribosomal RNA small subunit methyltransferase H HAMAP MF_01007
PRO_0000386994

Regions

Region39 – 413S-adenosyl-L-methionine binding By similarity

Sites

Binding site581S-adenosyl-L-methionine By similarity
Binding site1061S-adenosyl-L-methionine By similarity
Binding site1131S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1B6W3 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 63620AD92E6E2B40

FASTA32435,224
        10         20         30         40         50         60 
MEHIPVLLDR CVELLTPALT RRNPDGRGAV LVDATLGAGG HAHRFLSDLP GLHLIGLDRD 

        70         80         90        100        110        120 
PQALQIAGER LAPFGDRVSL VRTRYDGIDD ALAQTGVAEV SGFLFDLGVS SMQLDRTERG 

       130        140        150        160        170        180 
FSYSADAPLD MRMDSDAPLT AADVVNTFAE KDITRILREF GEERFAARIA KHIVRRRPLN 

       190        200        210        220        230        240 
TTGELVELLY DAIPAPARRT GGHPAKRTFQ ALRIAVNSEL DSLRAAVPAA LAALETGGRI 

       250        260        270        280        290        300 
VVMAYQSLED RIVKTEFAAA TASRTPPGLP VELPGHEPEF VALTRGAERA TPEEIERNPR 

       310        320 
SAPVRLRALE KVAGRPTTAR RDAR

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium sp. MCS."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. expand/collapse author list , Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MCS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000384 Genomic DNA. Translation: ABG09371.1.
RefSeqYP_640427.1. NC_008146.1.

3D structure databases

ProteinModelPortalQ1B6W3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1B6W3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000059307; EBMYCP00000057474; EBMYCG00000059302.
GeneID4112096.
GenomeReviewsGene locus Mmcs_3264 in contig CP000384_GR.
KEGGmmc:Mmcs_3264.
PATRIC18116807. VBIMycSp106721_3345.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0275.
GeneTreeEBGT00050000016736.
HOGENOMHBG302779.
OMANPATRAF.
ProtClustDBPRK00050.

Enzyme and pathway databases

BioCycMSP164756:MMCS_3264-MONOMER.

Family and domain databases

HAMAPMF_01007. 16SrRNA_methyltr_H.
[Tree]
InterProIPR002903. SAM-dep_MeTrfase_MraW.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
[Graphical view]
Gene3DG3DSA:1.10.150.170. G3DSA:1.10.150.170. 1 hit.
KOK03438.
PANTHERPTHR11265. Bact_methyltrans. 1 hit.
PfamPF01795. Methyltransf_5. 1 hit.
[Graphical view]
PIRSFPIRSF004486. MraW. 1 hit.
SUPFAMSSF81799. SSF81799. 1 hit.
TIGRFAMsTIGR00006. TIGR00006. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMH_MYCSS
AccessionPrimary (citable) accession number: Q1B6W3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: July 11, 2006
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents