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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium sp. (strain MCS)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mmcs_3898
OrganismiMycobacterium sp. (strain MCS)
Taxonomic identifieri164756 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180711 – 550Arginine--tRNA ligaseAdd BLAST550

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1B531
SMRiQ1B531
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q1B531-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPADLADLL RTTATAVLTE RDLDTAALPA TVTVERPRNP EHGDYATNLA
60 70 80 90 100
LQVGKKVGVN PRELAGWLAE ALTATAGIAS AEVAGPGFVN LRIEAAAQNV
110 120 130 140 150
IVGDIITSAE RYGHSAALAE RNINLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLATQGAA VVREYYFNDH GAQIDRFVSS LIAAAKGEPT PEDGYAGSYI
210 220 230 240 250
GDIAAQVLAK DPGALELPDD EMRETFRAIG VDLMFDHIKI SLHDFGTDFD
260 270 280 290 300
VFTHEDSMHT SGRVEEAIAR LRENGAIYEK DGATWLRTTD FGDDKDRVVI
310 320 330 340 350
KSDGAPAYIA GDLAYFLDKR QRGFDLCIYM LGADHHGYIA RLKAAAAALG
360 370 380 390 400
DDPDTVEVMI GQMVNLVRDG QPVRMSKRAG TVITLDDLVE AIGVDAARYS
410 420 430 440 450
LIRSSVDTPI DIDLALWSSA SNENPVYYVQ YAHARLSALA RNAADLGVVA
460 470 480 490 500
DTAHLDLLTH DKEGTLIRNL GEFPRVLESA AALREPHRVC RYLEDLAGDY
510 520 530 540 550
HRFYDSCRVL PQGDEAPGSL HQARLALCQA TRQVIANGLA ILGVSAPERM
Length:550
Mass (Da):59,279
Last modified:July 11, 2006 - v1
Checksum:i136642AEFAC21D04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000384 Genomic DNA Translation: ABG10003.1
RefSeqiWP_011561278.1, NC_008146.1

Genome annotation databases

EnsemblBacteriaiABG10003; ABG10003; Mmcs_3898
GeneIDi32418950
KEGGimmc:Mmcs_3898

Similar proteinsi

Entry informationi

Entry nameiSYR_MYCSS
AccessioniPrimary (citable) accession number: Q1B531
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: February 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program