Reviewed, UniProtKB/Swiss-Prot Q1B510 (CYSD_MYCSS)

Names and origin

Protein names

Recommended name:
    Sulfate adenylyltransferase subunit 2
    EC=2.7.7.4
Alternative name(s):
    Sulfate adenylate transferase
      Short name=SAT
    ATP-sulfurylase small subunit

Gene names

Name:	cysD
Ordered Locus Names:	Mmcs_3919

Organism

Mycobacterium sp. (strain MCS) [Complete proteome] [HAMAP]

Taxonomic identifier

164756 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of cysD, the smaller subunit, and cysN By similarity. HAMAP MF_00064
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000092211

Sequences

	Sequence		Length	Mass (Da)
	Q1B510-1 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: EBA28E7772AFCF98	FASTA	309	34,950
	10 20 30 40 50 60 MTAAHVAAPE PGQYELSHLR LLEAEAIHII REVAAEFERP VLLFSGGKDS IVMLHLAIKA 70 80 90 100 110 120 FAPARLPFPV MHVDTGHNFD EVISTRDRLV AENGVRLVVA SVQEDIDAGR VVDNGPSRNP 130 140 150 160 170 180 LQTITLLRAI RENRFDAAFG GARRDEEKAR AKERVFSFRD EFGQWDPKAQ RPELWNIYNG 190 200 210 220 230 240 RHRKGEHIRV FPLSNWTEYD IWAYIGAEGI TLPGIYYAHT RPVFQRDGML LAVHPYMQPR 250 260 270 280 290 300 DDEEVFETSV RFRTVGDVTC TGCVESTAST VEDIIAETAV SRLTERGATR ADDRISEAGM EDRKREGYF

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. MCS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000384 Genomic DNA. Translation: ABG10024.1.
RefSeq	YP_641080.1.
3D structure databases
SMR	Q1B510. Positions 14-267.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1B510.
Genome annotation databases
GeneID	4112749.
GenomeReviews	Gene locus Mmcs_3919 in contig CP000384_GR.
KEGG	mmc:Mmcs_3919.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	PPIYYAH.
Enzyme and pathway databases
BioCyc	MSP164756:MMCS_3919-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_MYCSS

Accession

Primary (citable) accession number: Q1B510

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 11, 2006
Last modified:	February 9, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)