Q1B4N5 (PHS_MYCSS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

Mmcs_4044

Organism

Mycobacterium sp. (strain MCS) [Complete proteome] [HAMAP]

Taxonomic identifier

164756 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000050425

Sequences

	Sequence		Length	Mass (Da)
	Q1B4N5 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 16A32F9850AD9B02	FASTA	94	10,609
	10 20 30 40 50 60 MAVLTDDQVD AALPELGGWE RADGALRRSV KFPAFLDGIE AVRRVAERAE AKDHHPDIDI 70 80 90 RWRTVTFVLV THSEGGITEK DLQMAREIDE ILDR

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. MCS." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MCS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000384 Genomic DNA. Translation: ABG10149.1.
RefSeq	YP_641205.1. NC_008146.1.
3D structure databases
ProteinModelPortal	Q1B4N5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1B4N5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000063878; EBMYCP00000062045; EBMYCG00000063873.
GeneID	4112874.
GenomeReviews	Gene locus Mmcs_4044 in contig CP000384_GR.
KEGG	mmc:Mmcs_4044.
PATRIC	18118427. VBIMycSp106721_4143.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2154.
GeneTree	EBGT00050000016936.
HOGENOM	HBG705804.
OMA	EHAESKD.
ProtClustDB	PRK00823.
Enzyme and pathway databases
BioCyc	MSP164756:MMCS_4044-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_MYCSS

Accession

Primary (citable) accession number: Q1B4N5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 11, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program