Q1B3U3 (Q1B3U3_MYCSS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA-formamidopyrimidine glycosylase EMBL ABG10441.1
EC=3.2.2.23 EMBL ABG10441.1

Gene names

Ordered Locus Names:

Mmcs_4336 EMBL ABG10441.1

Organism

Mycobacterium sp. (strain MCS) [Complete proteome] [HAMAP] EMBL ABG10441.1

Taxonomic identifier

164756 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. SAAS SAAS015886
Cofactor	Binds 1 zinc ion per subunit By similarity. SAAS SAAS015886
Sequence similarities	Contains 1 FPG-type zinc finger. SAAS SAAS015886

Ontologies

Keywords
Biological process	DNA damage DNA repair SAAS SAAS015886
Domain	Zinc-finger SAAS SAAS015886
Ligand	DNA-binding SAAS SAAS015886 Metal-binding Zinc
Molecular function	Glycosidase SAAS SAAS015886 EMBL ABG10441.1 Hydrolase Lyase SAAS SAAS015886
Technical term	Complete proteome Multifunctional enzyme SAAS SAAS015886
Gene Ontology (GO)
Biological_process	base-excision repair Inferred from electronic annotation. Source: InterPro nucleotide-excision repair Inferred from electronic annotation. Source: InterPro
Molecular_function	damaged DNA binding Inferred from electronic annotation. Source: InterPro oxidized purine nucleobase lesion DNA N-glycosylase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1B3U3 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: D0CBB5AA7BBD835F	FASTA	287	30,617
	10 20 30 40 50 60 MPELPEVEAL ADHLRRHAVG LPIGRVDVSA FSVLKTFDPP ITALHGREVT DAHRWGKYLG 70 80 90 100 110 120 LQAGDLYLIT HLSRAGWLRW SDKLAAAPLK PGKGPIALRV HLGTPGAAPG FDLTEAGTQK 130 140 150 160 170 180 RLAVWLVSDP SAVPGIAALG PDALELTADE LGVLLSKQSG RIKTVITDQK VLAGIGNAYS 190 200 210 220 230 240 DEILHVAQLS PFATANKLTP EQVATLHDAM LSVLTDAVSR SVGQQAATLK GEKRSGLRVH 250 260 270 280 ARTGLPCPVC GDTVREVSFA DKSFQYCPTC QTGGRVLADR RLSRLLK

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. MCS." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Miller C.D., Hughes J.E., Anderson A.J., Sims R.C., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MCS EMBL ABG10441.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000384 Genomic DNA. Translation: ABG10441.1.
RefSeq	YP_641497.1. NC_008146.1.
3D structure databases
ProteinModelPortal	Q1B3U3.
ModBase	Search...
Protein-protein interaction databases
STRING	164756.Mmcs_4336.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABG10441; ABG10441; Mmcs_4336.
GeneID	4113166.
KEGG	mmc:Mmcs_4336.
PATRIC	18119021. VBIMycSp106721_4437.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0266.
HOGENOM	HOG000020886.
KO	K10563.
OMA	HLMIAGR.
ProtClustDB	CLSK902035.
Enzyme and pathway databases
BioCyc	MSP164756:GHQ8-4622-MONOMER.
Family and domain databases
InterPro	IPR015886. DNA_glyclase/AP_lyase_DNA-bd. IPR012319. DNA_glycosylase/AP_lyase_cat. IPR010979. Ribosomal_S13-like_H2TH. IPR000214. Znf_DNA_glyclase/AP_lyase. IPR010663. Znf_DNA_glyclase/IsotRNA_synth. [Graphical view]
Pfam	PF01149. Fapy_DNA_glyco. 1 hit. PF06831. H2TH. 1 hit. PF06827. zf-FPG_IleRS. 1 hit. [Graphical view]
SMART	SM00898. Fapy_DNA_glyco. 1 hit. [Graphical view]
SUPFAM	SSF81624. Form_DNAglyc_cat. 1 hit. SSF46946. Ribosomal_H2TH. 1 hit.
PROSITE	PS51068. FPG_CAT. 1 hit. PS51066. ZF_FPG_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1B3U3_MYCSS

Accession

Primary (citable) accession number: Q1B3U3

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)