ID   Q1AX94_RUBXD            Unreviewed;       652 AA.
AC   Q1AX94;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   24-JAN-2024, entry version 83.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ABG03984.1};
GN   OrderedLocusNames=Rxyl_1018 {ECO:0000313|EMBL:ABG03984.1};
OS   Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1).
OC   Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales; Rubrobacteraceae;
OC   Rubrobacter.
OX   NCBI_TaxID=266117 {ECO:0000313|EMBL:ABG03984.1, ECO:0000313|Proteomes:UP000006637};
RN   [1] {ECO:0000313|EMBL:ABG03984.1, ECO:0000313|Proteomes:UP000006637}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 9941 / NBRC 16129 / PRD-1
RC   {ECO:0000313|Proteomes:UP000006637};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S.,
RA   Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.;
RT   "Complete sequence of Rubrobacter xylanophilus DSM 9941.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000386; ABG03984.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1AX94; -.
DR   STRING; 266117.Rxyl_1018; -.
DR   KEGG; rxy:Rxyl_1018; -.
DR   eggNOG; COG2199; Bacteria.
DR   eggNOG; COG2206; Bacteria.
DR   HOGENOM; CLU_420268_0_0_11; -.
DR   Proteomes; UP000006637; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00277; HDIG; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   PANTHER; PTHR45228:SF4; LIPOPROTEIN-RELATED; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS51831; HD; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABG03984.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006637};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          341..463
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          458..652
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          480..602
FT                   /note="HD"
FT                   /evidence="ECO:0000259|PROSITE:PS51831"
SQ   SEQUENCE   652 AA;  68220 MW;  A03D99987DC785A6 CRC64;
     MRSGSVPGEP LTTGLLRAVA GAALFALLAA GLGEGAAAYA GAALLAGFGL LWASGRPRRL
     LGEPLVPLLA DACAVSLLVL GTGGPGSPLL PLYFLAALGL VRAGETWRQV AGGGALVGGF
     LAAAWPVPAP ALLGAGMLAA FCCGAAALGR ELRGLSGRGR ELAARAAEER ELAGRLAALG
     ERLGPVLGML EPERVLEWAA GTARDLCGAA YAHAVLLDGN VHRTSMGGDF PACPTWWHPA
     VQELVLRGAR GGETVRRPGL EVHGLEGFIA VPVEAPGGGA LVVGGGRFGE VEERLLRALA
     GQLCAALQDG GGAPGGRDAV TGLPNRASLH RVLRKELAYG GAAGVVSLRL GGLEDYARSQ
     GMALSEALVR RIAGRLAGRH RAFRYGVDEF CLLVRGADED RARGVARWAL DVVREVAGDL
     EASAGYAVSS GGARGPEELL ALARRPLPEG GGEARRGLEV EVREVVEALH EAASVRDPEL
     GEHMREVSRI ARRVGERLGL SPQELEALTY GALLHDIGKL GVPDAILNKP SALSPREYEA
     VKRHTEHGAR ILRRVRALSE AMLAVRHHHE RFDGAGYPDG LQGADIPLLA RIVFVADAFD
     SMTRSRPYRG GASRREALRE IAHNSGSQFD PRVVDALFEV MEELGRRRSA SA
//