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Q1AX49 (Q1AX49_RUBXD) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP-Rule MF_00186
EC=2.7.1.30 HAMAP-Rule MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP-Rule MF_00186
Glycerokinase HAMAP-Rule MF_00186
Gene names
Name:glpK HAMAP-Rule MF_00186
Ordered Locus Names:Rxyl_1063
OrganismRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) [Complete proteome] [HAMAP] EMBL ABG04029.1
Taxonomic identifier266117 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Rubrobacteridae › Rubrobacterales › Rubrobacterineae › Rubrobacteraceae › Rubrobacter ›

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP-Rule MF_00186 SAAS SAAS018484

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP-Rule MF_00186 SAAS SAAS018484

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP-Rule MF_00186 SAAS SAAS018484

Sequence similarities

Belongs to the FGGY kinase family. HAMAP-Rule MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding412 – 4165ATP By similarity HAMAP-Rule MF_00186

Sites

Binding site131Substrate By similarity HAMAP-Rule MF_00186
Binding site831Substrate By similarity HAMAP-Rule MF_00186
Binding site1351Substrate By similarity HAMAP-Rule MF_00186
Binding site2451Substrate By similarity HAMAP-Rule MF_00186
Binding site2671ATP By similarity HAMAP-Rule MF_00186
Binding site3111ATP; via carbonyl oxygen By similarity HAMAP-Rule MF_00186

Sequences

Sequence LengthMass (Da)Tools
Q1AX49 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 4F3ED0F1C4121F56

FASTA50355,499
        10         20         30         40         50         60 
MAGEYVLAID QGTTGTTVLI FDREGRVAGR AYSEFTQHYP RPGWVEHDPN EIWDVSMRVV 

        70         80         90        100        110        120 
GEALGDAKVS ARQLAAIGIT NQRETTVMWD RRTGEPVANA IVWQDRRTAG TCDRLKDEGL 

       130        140        150        160        170        180 
EETFRKKTGL VIDAYFSGTK VKWFLDNVAG LRERAGRGEV AFGTVDSWLV YRLTGGRAHI 

       190        200        210        220        230        240 
TDYSNASRTL MYNIYDLRWD EELLEILGVP EGVLPEVKPS SHVYGETDPG AFFQASVPVA 

       250        260        270        280        290        300 
GIAGDQQAAL FGQAAYERGL AKNTYGTGSF VLMNTGNEAV PSKEGLLTTI AWGIGEEPVE 

       310        320        330        340        350        360 
YALEGAIFIT GAAVQWLRDG LGIIRSAAET EELAKSVQSN DGVYFVPALV GLGAPHWDAY 

       370        380        390        400        410        420 
ARGTIVGITR GTTKAHLARA ALESMCYQTL DVVRAMERDS GIELKELRAD GGAVANSFLM 

       430        440        450        460        470        480 
QFQSDILGVP VEVPEITETT ALGSAYLAGL ATGFWESREE LDARWRLSRR YEPSMQEGER 

       490        500 
ERLHRRWLRA VERSRGWDRE EEG

« Hide

References

[1]"Complete sequence of Rubrobacter xylanophilus DSM 9941."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S., Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 9941 / NBRC 16129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000386 Genomic DNA. Translation: ABG04029.1.
RefSeqYP_643841.1. NC_008148.1.

3D structure databases

ProteinModelPortalQ1AX49.
SMRQ1AX49. Positions 1-502.
ModBaseSearch...

Protein-protein interaction databases

STRING266117.Rxyl_1063.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG04029; ABG04029; Rxyl_1063.
GeneID4116943.
KEGGrxy:Rxyl_1063.
PATRIC23368972. VBIRubXyl52678_1091.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHOG000222134.
KOK00864.
OMACAVEACH.
ProtClustDBCLSK755211.

Enzyme and pathway databases

BioCycRXYL266117:GH8O-1080-MONOMER.
UniPathwayUPA00618; UER00672.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
InterProIPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
PANTHERPTHR10196:SF9. PTHR10196:SF9. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1AX49_RUBXD
AccessionPrimary (citable) accession number: Q1AX49
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: May 29, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info