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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei137GTPUniRule annotation1
Binding sitei141GTPUniRule annotation1
Binding sitei185GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 23GTPUniRule annotation5
Nucleotide bindingi106 – 108GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciRXYL266117:G1G6P-1518-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Rxyl_1489Imported
OrganismiRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)Imported
Taxonomic identifieri266117 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaRubrobacteriaRubrobacteralesRubrobacteraceaeRubrobacter
Proteomesi
  • UP000006637 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi266117.Rxyl_1489

Structurei

3D structure databases

ProteinModelPortaliQ1AVX7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 203TubulinInterPro annotationAdd BLAST193
Domaini205 – 322Tubulin_CInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili77 – 97Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1AVX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDAGTSYLA VIKVVGIGGG GTNAVNRMIN SGLQGVEFIA INTDAQALQM
60 70 80 90 100
CDADQKIHIG EKITRGLGAG ADPKIGMEAA EESKAEIEEA LRGADMVFVT
110 120 130 140 150
AGKGGGTGTG AAPVVAKIAR EAGALTVGVV TRPFSFEGRR RATYAEEGIK
160 170 180 190 200
KLKENVDSLI IIPNDRLLQV AEKRTSMMEA FKMADDILRK GVQGITDLIT
210 220 230 240 250
VPGLINLDFA DVRTIMQNSG SALMGIGESS SENRGAEAAR LAISSPLLEA
260 270 280 290 300
SIEGATGIIL NITGGPELGL FEVNEAAEIV HNAAHQDANL IFGAVIDESF
310 320 330 340 350
GDKVSVTVIA TGFDQRLANQ RRIERPVAET PPRPSEEEPR PQQEDGDVLD

IPAFLRRR
Length:358
Mass (Da):37,828
Last modified:July 11, 2006 - v1
Checksum:iDA23718A570D8D68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000386 Genomic DNA Translation: ABG04451.1
RefSeqiWP_011564468.1, NC_008148.1

Genome annotation databases

EnsemblBacteriaiABG04451; ABG04451; Rxyl_1489
KEGGirxy:Rxyl_1489

Similar proteinsi

Entry informationi

Entry nameiQ1AVX7_RUBXD
AccessioniPrimary (citable) accession number: Q1AVX7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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