Q1AUL7 (Q1AUL7_RUBXD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA topoisomerase RuleBase RU000518
EC=5.99.1.2 RuleBase RU000518

Gene names

Ordered Locus Names:

Rxyl_1964

Organism

Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) [Complete proteome] [HAMAP]

Taxonomic identifier

266117 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Rubrobacteridae › Rubrobacterales › Rubrobacterineae › Rubrobacteraceae › Rubrobacter

Protein attributes

Sequence length	702 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP-independent breakage of single-stranded DNA, followed by passage and rejoining. RuleBase RU000518 SAAS SAAS013825
Sequence similarities	Belongs to the prokaryotic type I/III topoisomerase family. RuleBase RU004206 Contains 1 Toprim domain. SAAS SAAS013825

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS013825 DNA-binding RuleBase RU000518 SAAS SAAS013825 Nucleotide-binding
Molecular function	Isomerase Topoisomerase RuleBase RU000518 SAAS SAAS013825
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase type I activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1AUL7 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: DCE23FF11AEA7E7B	FASTA	702	78,373
	10 20 30 40 50 60 MRLIISEKAN AARKIAQFLA EGPVKEGKHR SVPYHTFTWR GEECVSVGLK GHVLNPEYPE 70 80 90 100 110 120 EYSNWQKVDP RELIDARILK SVSEKGVAAA VRSLAKKADR VIIATDFDRE GELIGVEALS 130 140 150 160 170 180 LAFEANPALM DHVERARFSA LTKGEVTRAF ENLVEVSREL ADAGEARQDI DLIWGATLTR 190 200 210 220 230 240 WVSRAVKRYG SAFLSVGRVQ SPTLVLIAER ELERRAFVPE PYWEVEARLQ NGGGPFVARH 250 260 270 280 290 300 ARGRFKEEAE ARRALENLSE TAVVTEVRQR EATRPAPAPF NTTAFLTAAA NIGVSPSRAA 310 320 330 340 350 360 RIAEDLYTEG YISYPRTDNT VYPESLDLRE VLGFLAEVEG VGDYAGRLLG AGRLTPTRGR 370 380 390 400 410 420 RQTTDHPPIY PTGRASRAEL REDQWKIYQL VVRRFLATLS GPAKTLRTTL RFESGGEPLV 430 440 450 460 470 480 AGGTVVTEEG WLAVYHYGRR RDEELPRLSE GDEVRVAEAE LLAKETQPPG RYGQGRLIRL 490 500 510 520 530 540 MEDLGLGTKA TRPGIIQNLY DRGYIHGDPI VPTETGMAVA KALKDFASEI ASHEMTARLE 550 560 570 580 590 600 KSMDAISEGR VSKDSVVEES RELLRRVYDH LESSEEKFAD IVWNGIRGDE TLGPCPNCGR 610 620 630 640 650 660 NLVVRRNRRN RKRFAGCEGY PECRTTFPLP QKGDIIPLGT ACEACGLPEI KVLGGRRPWV 670 680 690 700 TCINMDCPKK QEQRRSREET QAGGEEPSEG QRDRKRLEKS TT

References

[1]

"Complete sequence of Rubrobacter xylanophilus DSM 9941." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S., Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 9941 / NBRC 16129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000386 Genomic DNA. Translation: ABG04911.1.
RefSeq	YP_644723.1. NC_008148.1.
3D structure databases
ProteinModelPortal	Q1AUL7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1AUL7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4115756.
GenomeReviews	Gene locus Rxyl_1964 in contig CP000386_GR.
KEGG	rxy:Rxyl_1964.
NMPDR	fig|266117.6.peg.1729.
PATRIC	23370732. VBIRubXyl52678_1956.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0550.
HOGENOM	HBG512935.
OMA	DKLVGYK.
PhylomeDB	Q1AUL7.
ProtClustDB	PRK07220.
Enzyme and pathway databases
BioCyc	RXYL266117:RXYL_1964-MONOMER.
Family and domain databases
InterPro	IPR000380. Topo_IA. IPR003601. Topo_IA_2. IPR023406. Topo_IA_AS. IPR013497. Topo_IA_cen. IPR013824. Topo_IA_cen_sub1. IPR013825. Topo_IA_cen_sub2. IPR023405. Topo_IA_core_domain. IPR003602. Topo_IA_DNA-bd. IPR013498. Topo_IA_Znf. IPR005739. TopoI_arch. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:1.10.460.10. Topo_IA_cen_sub1. 2 hits. G3DSA:2.70.20.10. Topo_IA_cen_sub2. 2 hits.
KO	K03168.
PANTHER	PTHR11390. Topo_IA. 1 hit.
Pfam	PF01131. Topoisom_bac. 1 hit. PF01751. Toprim. 1 hit. PF01396. zf-C4_Topoisom. 1 hit. [Graphical view]
PRINTS	PR00417. PRTPISMRASEI.
SMART	SM00437. TOP1Ac. 1 hit. SM00436. TOP1Bc. 1 hit. SM00493. TOPRIM. 1 hit. [Graphical view]
SUPFAM	SSF56712. Topo_IA_core. 1 hit.
TIGRFAMs	TIGR01057. TopA_arch. 1 hit.
PROSITE	PS00396. TOPOISOMERASE_I_PROK. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1AUL7_RUBXD

Accession

Primary (citable) accession number: Q1AUL7

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)