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Q1AUH7

- PGK_RUBXD

UniProt

Q1AUH7 - PGK_RUBXD

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Protein
Phosphoglycerate kinase
Gene
pgk, Rxyl_2004
Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei117 – 1171Substrate By similarity
Binding sitei150 – 1501Substrate By similarity
Binding sitei200 – 2001ATP By similarity
Binding sitei288 – 2881ATP; via carbonyl oxygen By similarity
Binding sitei319 – 3191ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi345 – 3484ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRXYL266117:GH8O-2041-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Rxyl_2004
OrganismiRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Taxonomic identifieri266117 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaRubrobacteridaeRubrobacteralesRubrobacterineaeRubrobacteraceaeRubrobacter
ProteomesiUP000006637: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Phosphoglycerate kinaseUniRule annotation
PRO_1000009645Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi266117.Rxyl_2004.

Structurei

3D structure databases

ProteinModelPortaliQ1AUH7.
SMRiQ1AUH7. Positions 2-390.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1AUH7-1 [UniParc]FASTAAdd to Basket

« Hide

MDKRSVRDLE LRGKKVLVRV DFNVPVKGGE VTDDTRIRRA LPTIRYLLQR    50
GARVALISHL GRPKGEPDPR YRMDPVARRL EELLGEPVRK LDTATGPEVG 100
RALEELERGV ILLENSRFYP GETKNDPAFA AELAGPFDLY VNDAFGAAHR 150
AHATTVGVAE RLPAAAGFLL EQELDYLDGV LRSPERPFVA ILGGAKVSDK 200
LGVIESLLGV ADRLLVGGAM CFTFLKARGL GVGASLVEDD YLGEARRLME 250
GAADRLVLPV DVVVAERMEE GARTRTVPVE EIPEGWMGLD IGPRTVELFR 300
RHILQARTIF WNGPMGVFEI DAFARGTEGV ARAVAESGAT SVVGGGDSVA 350
AVRKLGLEDR MSHISTGGGA SLEYVEGREL PGVAVLPERE EV 392
Length:392
Mass (Da):42,491
Last modified:July 11, 2006 - v1
Checksum:iD34BFF1DB7075FB6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000386 Genomic DNA. Translation: ABG04951.1.
RefSeqiWP_011564966.1. NC_008148.1.
YP_644763.1. NC_008148.1.

Genome annotation databases

EnsemblBacteriaiABG04951; ABG04951; Rxyl_2004.
GeneIDi4117592.
KEGGirxy:Rxyl_2004.
PATRICi23370818. VBIRubXyl52678_1997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000386 Genomic DNA. Translation: ABG04951.1 .
RefSeqi WP_011564966.1. NC_008148.1.
YP_644763.1. NC_008148.1.

3D structure databases

ProteinModelPortali Q1AUH7.
SMRi Q1AUH7. Positions 2-390.
ModBasei Search...

Protein-protein interaction databases

STRINGi 266117.Rxyl_2004.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG04951 ; ABG04951 ; Rxyl_2004 .
GeneIDi 4117592.
KEGGi rxy:Rxyl_2004.
PATRICi 23370818. VBIRubXyl52678_1997.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci RXYL266117:GH8O-2041-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9941 / NBRC 16129.

Entry informationi

Entry nameiPGK_RUBXD
AccessioniPrimary (citable) accession number: Q1AUH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: September 3, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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