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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei283 – 2831Proton donorUniRule annotation
Active sitei304 – 3041UniRule annotation
Active sitei418 – 4181UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciRXYL266117:GH8O-2736-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Rxyl_2677
OrganismiRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Taxonomic identifieri266117 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaRubrobacteridaeRubrobacteralesRubrobacterineaeRubrobacteraceaeRubrobacter
ProteomesiUP000006637 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 432432Glucose-6-phosphate isomerasePRO_0000252643Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266117.Rxyl_2677.

Structurei

3D structure databases

ProteinModelPortaliQ1ASN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100402.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1ASN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADVTFDYRN LLEVEGGLTG RELEEISPRL RAAVGTLLED PPGFMRLPRT
60 70 80 90 100
REHLEASLEV AERVRSDGAT DFVHVGIGGS ALGPMVLHRA LSHPFYNLLP
110 120 130 140 150
DRGGPRLHFA ENADPATLSG ILDVIEPEGT WVNVVTKSGS TAETMANFLV
160 170 180 190 200
IRGALAEALG DFGYQARTVV TTDPEKGFLK RIADREDLVT LQVPPEVGGR
210 220 230 240 250
FSVLSPVGLL PAAVAGLDVE ALLAGAARCV EELEEQGAEH PAVVGAAMHH
260 270 280 290 300
LMDASRGRNI RVMMVYADAL ERLAAWFVQL WAESLGKDGK GSTPHGAVGT
310 320 330 340 350
TDQHSQLQLY MEGPQDKVIE IVEVREHPRD VGIPGAYEDL EGVGYLSGHT
360 370 380 390 400
VGELLNVECD ATRRALTGAG RPNATIRLGS LSAENLGYLM QALEVQTAVA
410 420 430
GALYGVNPYD QPGVEAGKRI TYARMGRPGY RA
Length:432
Mass (Da):46,340
Last modified:July 11, 2006 - v1
Checksum:i152FCE074C0DBEB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000386 Genomic DNA. Translation: ABG05594.1.
RefSeqiWP_011565603.1. NC_008148.1.
YP_645406.1. NC_008148.1.

Genome annotation databases

EnsemblBacteriaiABG05594; ABG05594; Rxyl_2677.
KEGGirxy:Rxyl_2677.
PATRICi23372150. VBIRubXyl52678_2647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000386 Genomic DNA. Translation: ABG05594.1.
RefSeqiWP_011565603.1. NC_008148.1.
YP_645406.1. NC_008148.1.

3D structure databases

ProteinModelPortaliQ1ASN4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266117.Rxyl_2677.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG05594; ABG05594; Rxyl_2677.
KEGGirxy:Rxyl_2677.
PATRICi23372150. VBIRubXyl52678_2647.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100402.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciRXYL266117:GH8O-2736-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9941 / NBRC 16129.

Entry informationi

Entry nameiG6PI_RUBXD
AccessioniPrimary (citable) accession number: Q1ASN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 11, 2006
Last modified: May 27, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.