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Q1ASN4 (G6PI_RUBXD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Rxyl_2677
OrganismRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) [Complete proteome] [HAMAP]
Taxonomic identifier266117 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Rubrobacteridae › Rubrobacterales › Rubrobacterineae › Rubrobacteraceae › Rubrobacter

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473

Subcellular location

Cytoplasm By similarity HAMAP MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 432432Glucose-6-phosphate isomerase HAMAP MF_00473
PRO_0000252643

Sites

Active site2831Proton donor By similarity
Active site3041 By similarity
Active site4181 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1ASN4 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 152FCE074C0DBEB1

FASTA43246,340
        10         20         30         40         50         60 
MADVTFDYRN LLEVEGGLTG RELEEISPRL RAAVGTLLED PPGFMRLPRT REHLEASLEV 

        70         80         90        100        110        120 
AERVRSDGAT DFVHVGIGGS ALGPMVLHRA LSHPFYNLLP DRGGPRLHFA ENADPATLSG 

       130        140        150        160        170        180 
ILDVIEPEGT WVNVVTKSGS TAETMANFLV IRGALAEALG DFGYQARTVV TTDPEKGFLK 

       190        200        210        220        230        240 
RIADREDLVT LQVPPEVGGR FSVLSPVGLL PAAVAGLDVE ALLAGAARCV EELEEQGAEH 

       250        260        270        280        290        300 
PAVVGAAMHH LMDASRGRNI RVMMVYADAL ERLAAWFVQL WAESLGKDGK GSTPHGAVGT 

       310        320        330        340        350        360 
TDQHSQLQLY MEGPQDKVIE IVEVREHPRD VGIPGAYEDL EGVGYLSGHT VGELLNVECD 

       370        380        390        400        410        420 
ATRRALTGAG RPNATIRLGS LSAENLGYLM QALEVQTAVA GALYGVNPYD QPGVEAGKRI 

       430 
TYARMGRPGY RA

« Hide

References

[1]"Complete sequence of Rubrobacter xylanophilus DSM 9941."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S., Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 9941 / NBRC 16129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000386 Genomic DNA. Translation: ABG05594.1.
RefSeqYP_645406.1. NC_008148.1.

3D structure databases

ProteinModelPortalQ1ASN4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1ASN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4115158.
GenomeReviewsGene locus Rxyl_2677 in contig CP000386_GR.
KEGGrxy:Rxyl_2677.
NMPDRfig|266117.6.peg.2335.
PATRIC23372150. VBIRubXyl52678_2647.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHBG615843.
OMAEHINITE.
ProtClustDBPRK00973.

Enzyme and pathway databases

BioCycRXYL266117:RXYL_2677-MONOMER.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
[Tree]
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
KOK01810.
PANTHERPTHR11469. G6P_Isomerase. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. False negative.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RUBXD
AccessionPrimary (citable) accession number: Q1ASN4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 11, 2006
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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