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Q1AS71 (ALLB_RUBXD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Ordered Locus Names:Rxyl_2845
OrganismRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) [Complete proteome] [HAMAP]
Taxonomic identifier266117 [NCBI]
Taxonomic lineageBacteriaActinobacteriaRubrobacteridaeRubrobacteralesRubrobacterineaeRubrobacteraceaeRubrobacter

Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Allantoinase HAMAP-Rule MF_01645
PRO_0000317681

Sites

Metal binding601Zinc 1 By similarity
Metal binding621Zinc 1 By similarity
Metal binding1471Zinc 1; via carbamate group By similarity
Metal binding1471Zinc 2; via carbamate group By similarity
Metal binding1831Zinc 2 By similarity
Metal binding2391Zinc 2 By similarity
Metal binding3121Zinc 1 By similarity

Amino acid modifications

Modified residue1471N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1AS71 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 49772AD22B3E7307

FASTA45448,161
        10         20         30         40         50         60 
MSAFDLIVRG GTVVRGGCEV ADVGVADGVI SAVGPDLEGG AREEIDARGL LVLPGAIDAH 

        70         80         90        100        110        120 
VHFNEPGRTR WEGFASGTRA LAAGGTTLCV EMPLNAHPPT TDGESFDLKL AAAKASAHVD 

       130        140        150        160        170        180 
FALWGGIVPG RVGRMEELAG RGVAGFKAFM SATGTPDFEA ADDLTLYEGM QEAARLGLPV 

       190        200        210        220        230        240 
LVHAENRQIT DALARRATSA LRTTMRDYLA SRPAVAELEA IGRAILLASE AGCSLHIVHV 

       250        260        270        280        290        300 
STGRGVALVA AARERGVDVT CETCPHYLLF TDEDAVRIGA AAKCAPPLRP REEVESLWEQ 

       310        320        330        340        350        360 
VLAGNVAFVT SDHSPCPPDM KAGEDMFRAW GGISGCQSLL PALLDEGYHG RGLPPERLAE 

       370        380        390        400        410        420 
LLSANVARRF GFAGKGGIEE GNDADLALVD PSGEHVLREE DLHYRHPISP YVGRSFRGRV 

       430        440        450 
VRTILRGRTV FEGGRVVSGP AGRFVRPQRE KGER 

« Hide

References

[1]"Complete sequence of Rubrobacter xylanophilus DSM 9941."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S., Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 9941 / NBRC 16129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000386 Genomic DNA. Translation: ABG05757.1.
RefSeqYP_645569.1. NC_008148.1.

3D structure databases

ProteinModelPortalQ1AS71.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266117.Rxyl_2845.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG05757; ABG05757; Rxyl_2845.
GeneID4115822.
KEGGrxy:Rxyl_2845.
PATRIC23372490. VBIRubXyl52678_2817.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0044.
HOGENOMHOG000219146.
KOK01466.
OMAHAEMIPP.
OrthoDBEOG6KHFW6.

Enzyme and pathway databases

BioCycRXYL266117:GH8O-2905-MONOMER.
UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 1 hit.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
TIGR00857. pyrC_multi. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_RUBXD
AccessionPrimary (citable) accession number: Q1AS71
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 11, 2006
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways