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Q1AS52 (Q1AS52_RUBXD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401
Gene names
Name:msrA HAMAP MF_01401
Ordered Locus Names:Rxyl_2864
OrganismRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) [Complete proteome] [HAMAP]
Taxonomic identifier266117 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Rubrobacteridae › Rubrobacterales › Rubrobacterineae › Rubrobacteraceae › Rubrobacter

Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site311 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q1AS52 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: A006FDF6899C5511

FASTA19722,633
        10         20         30         40         50         60 
MLRAGAGTPA AWYPQRRMDG RLETATLGGG CFWCVEAVFD ELRGVRRVEP GYSGGHVERP 

        70         80         90        100        110        120 
TYEQVCTGLT GHAEVVQVSF DPREISYREL LEVFFAVHDP TTKDRQGPDV GPQYRSVIFY 

       130        140        150        160        170        180 
HDEEQRRTAE EVISELEARG IWDGPIVTEV APFTAFYPAE EYHRDYFRRN PDQPYCRVVI 

       190 
APKVAKFRKE FLERLKA

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References

[1]"Complete sequence of Rubrobacter xylanophilus DSM 9941."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., da Costa M.S., Rainey F.A., Empadinhas N., Jolivet E., Battista J.R., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 9941 / NBRC 16129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000386 Genomic DNA. Translation: ABG05776.1.
RefSeqYP_645588.1. NC_008148.1.

3D structure databases

ProteinModelPortalQ1AS52.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1AS52.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4115861.
GenomeReviewsGene locus Rxyl_2864 in contig CP000386_GR.
KEGGrxy:Rxyl_2864.
NMPDRfig|266117.6.peg.2503.
PATRIC23372530. VBIRubXyl52678_2836.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMAPYCRFVI.
PhylomeDBQ1AS52.
ProtClustDBPRK14054.

Enzyme and pathway databases

BioCycRXYL266117:RXYL_2864-MONOMER.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1AS52_RUBXD
AccessionPrimary (citable) accession number: Q1AS52
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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