SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1AR71

- SYL_RUBXD

UniProt

Q1AR71 - SYL_RUBXD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, Rxyl_3202
Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei591 – 5911ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRXYL266117:GH8O-3266-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:Rxyl_3202
OrganismiRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Taxonomic identifieri266117 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaRubrobacteridaeRubrobacteralesRubrobacterineaeRubrobacteraceaeRubrobacter
ProteomesiUP000006637: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 817817Leucine--tRNA ligaseUniRule annotation
PRO_0000334808Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266117.Rxyl_3202.

Structurei

3D structure databases

ProteinModelPortaliQ1AR71.
SMRiQ1AR71. Positions 13-752.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi51 – 6111"HIGH" regionUniRule annotation
Add
BLAST
Motifi588 – 5925"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1AR71-1 [UniParc]FASTAAdd to Basket

« Hide

MSETFAKRAS RRGYDPRAIE ERWQRRWAET GLYKTDEDPS KPKHYALTML    50
PYPSGDLHVG HWYAMTPSDT RARFMRMRGY RVFFPIGFDA FGLPAENAAI 100
KRGIHPRDWT YSNIERMRGQ LRQMGTMFDF DAEVVTCDPE YYRWNQWFFL 150
KFYEKGLAYR EKAPVDWCPS CNTTLAREQV VGPDRRCERC DTPVIKRNLA 200
QWLFKITDYA EELLDFSEIE WPERVKALQR NWIGRSEGAE IEFEIEGYGG 250
VTVFTTRPDT LFGATFFVVA PEHPAVESIT TPERGEEVRA YVERAARMSE 300
IDRADVTREK TGVFTGAYAV NPANGERIPV YVADYVLMGY GTGAIMAVPA 350
HDERDFEFAK KHGIEIRTVI APPDWDGSPL ERAYVGEGQM VNSGPFDGTP 400
SAEGREKVTG WLRERGVGRP AVNYRLRDWL ISRQRYWGTP IPIVYCERCG 450
TVPVPEEDLP VLLPEDAEFM PTGESPLKFN DEFRKTECPR CGGPAERETD 500
TMDTFVDSSW YQYRYLSPHY EEGPFDPERG SRWLPVDQYT GGIEHATMHL 550
LYTRFFTKVM RDLGLVDFDE PMLRLFNQGV ILGPDGNRMS KSRGNVVNPQ 600
EYVDRYGSDV LRCYLMFIGP WDEGGPWDPG GIEGVARWLR RAFTLVAGGD 650
VSEAEADPGE LSRRTHRLVK RVTEYLEGFR FNTAIAALME HTNYLLAVKG 700
EVGEEEWREA MRSFLLVLAP FAPHHAEEMW EILGEEYSVH EQGWPSWDEE 750
LVREETVTLV VQVNGKLRDR VEAPAGVDEG RARELALSSE RVRAHVEGRE 800
LRKTVYVPGR LINLVVS 817
Length:817
Mass (Da):93,833
Last modified:July 11, 2006 - v1
Checksum:iFDE42442A52BC7CD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000386 Genomic DNA. Translation: ABG06107.1.
RefSeqiWP_011566112.1. NC_008148.1.
YP_645919.1. NC_008148.1.

Genome annotation databases

EnsemblBacteriaiABG06107; ABG06107; Rxyl_3202.
GeneIDi4114999.
KEGGirxy:Rxyl_3202.
PATRICi23373196. VBIRubXyl52678_3168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000386 Genomic DNA. Translation: ABG06107.1 .
RefSeqi WP_011566112.1. NC_008148.1.
YP_645919.1. NC_008148.1.

3D structure databases

ProteinModelPortali Q1AR71.
SMRi Q1AR71. Positions 13-752.
ModBasei Search...

Protein-protein interaction databases

STRINGi 266117.Rxyl_3202.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG06107 ; ABG06107 ; Rxyl_3202 .
GeneIDi 4114999.
KEGGi rxy:Rxyl_3202.
PATRICi 23373196. VBIRubXyl52678_3168.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci RXYL266117:GH8O-3266-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9941 / NBRC 16129.

Entry informationi

Entry nameiSYL_RUBXD
AccessioniPrimary (citable) accession number: Q1AR71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 11, 2006
Last modified: September 3, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi