Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q1AR71

- SYL_RUBXD

UniProt

Q1AR71 - SYL_RUBXD

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei591 – 5911ATPUniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA editing activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRXYL266117:GH8O-3266-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
    Alternative name(s):
    Leucyl-tRNA synthetaseUniRule annotation
    Short name:
    LeuRSUniRule annotation
    Gene namesi
    Name:leuSUniRule annotation
    Ordered Locus Names:Rxyl_3202
    OrganismiRubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
    Taxonomic identifieri266117 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaRubrobacteridaeRubrobacteralesRubrobacterineaeRubrobacteraceaeRubrobacter
    ProteomesiUP000006637: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 817817Leucine--tRNA ligasePRO_0000334808Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi266117.Rxyl_3202.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1AR71.
    SMRiQ1AR71. Positions 13-752.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi51 – 6111"HIGH" regionAdd
    BLAST
    Motifi588 – 5925"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0495.
    HOGENOMiHOG000200748.
    KOiK01869.
    OMAiHISHELW.
    OrthoDBiEOG63Z74X.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 2 hits.
    3.90.740.10. 1 hit.
    HAMAPiMF_00049_B. Leu_tRNA_synth_B.
    InterProiIPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view]
    PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
    PfamiPF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 1 hit.
    PF13603. tRNA-synt_1_2. 1 hit.
    [Graphical view]
    PRINTSiPR00985. TRNASYNTHLEU.
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsiTIGR00396. leuS_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1AR71-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSETFAKRAS RRGYDPRAIE ERWQRRWAET GLYKTDEDPS KPKHYALTML    50
    PYPSGDLHVG HWYAMTPSDT RARFMRMRGY RVFFPIGFDA FGLPAENAAI 100
    KRGIHPRDWT YSNIERMRGQ LRQMGTMFDF DAEVVTCDPE YYRWNQWFFL 150
    KFYEKGLAYR EKAPVDWCPS CNTTLAREQV VGPDRRCERC DTPVIKRNLA 200
    QWLFKITDYA EELLDFSEIE WPERVKALQR NWIGRSEGAE IEFEIEGYGG 250
    VTVFTTRPDT LFGATFFVVA PEHPAVESIT TPERGEEVRA YVERAARMSE 300
    IDRADVTREK TGVFTGAYAV NPANGERIPV YVADYVLMGY GTGAIMAVPA 350
    HDERDFEFAK KHGIEIRTVI APPDWDGSPL ERAYVGEGQM VNSGPFDGTP 400
    SAEGREKVTG WLRERGVGRP AVNYRLRDWL ISRQRYWGTP IPIVYCERCG 450
    TVPVPEEDLP VLLPEDAEFM PTGESPLKFN DEFRKTECPR CGGPAERETD 500
    TMDTFVDSSW YQYRYLSPHY EEGPFDPERG SRWLPVDQYT GGIEHATMHL 550
    LYTRFFTKVM RDLGLVDFDE PMLRLFNQGV ILGPDGNRMS KSRGNVVNPQ 600
    EYVDRYGSDV LRCYLMFIGP WDEGGPWDPG GIEGVARWLR RAFTLVAGGD 650
    VSEAEADPGE LSRRTHRLVK RVTEYLEGFR FNTAIAALME HTNYLLAVKG 700
    EVGEEEWREA MRSFLLVLAP FAPHHAEEMW EILGEEYSVH EQGWPSWDEE 750
    LVREETVTLV VQVNGKLRDR VEAPAGVDEG RARELALSSE RVRAHVEGRE 800
    LRKTVYVPGR LINLVVS 817
    Length:817
    Mass (Da):93,833
    Last modified:July 11, 2006 - v1
    Checksum:iFDE42442A52BC7CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000386 Genomic DNA. Translation: ABG06107.1.
    RefSeqiWP_011566112.1. NC_008148.1.
    YP_645919.1. NC_008148.1.

    Genome annotation databases

    EnsemblBacteriaiABG06107; ABG06107; Rxyl_3202.
    GeneIDi4114999.
    KEGGirxy:Rxyl_3202.
    PATRICi23373196. VBIRubXyl52678_3168.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000386 Genomic DNA. Translation: ABG06107.1 .
    RefSeqi WP_011566112.1. NC_008148.1.
    YP_645919.1. NC_008148.1.

    3D structure databases

    ProteinModelPortali Q1AR71.
    SMRi Q1AR71. Positions 13-752.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 266117.Rxyl_3202.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG06107 ; ABG06107 ; Rxyl_3202 .
    GeneIDi 4114999.
    KEGGi rxy:Rxyl_3202.
    PATRICi 23373196. VBIRubXyl52678_3168.

    Phylogenomic databases

    eggNOGi COG0495.
    HOGENOMi HOG000200748.
    KOi K01869.
    OMAi HISHELW.
    OrthoDBi EOG63Z74X.

    Enzyme and pathway databases

    BioCyci RXYL266117:GH8O-3266-MONOMER.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 2 hits.
    3.90.740.10. 1 hit.
    HAMAPi MF_00049_B. Leu_tRNA_synth_B.
    InterProi IPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view ]
    PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
    Pfami PF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 1 hit.
    PF13603. tRNA-synt_1_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00985. TRNASYNTHLEU.
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 1 hit.
    TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 9941 / NBRC 16129.

    Entry informationi

    Entry nameiSYL_RUBXD
    AccessioniPrimary (citable) accession number: Q1AR71
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3