Reviewed, UniProtKB/Swiss-Prot Q19V58 (NU1C_CHLAT)

Names and origin

Protein names

Recommended name:
    NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic
    EC=1.6.5.-
Alternative name(s):
    NAD(P)H dehydrogenase subunit 1
      Short name=NDH subunit 1
    NADH-plastoquinone oxidoreductase subunit 1

Gene names

Name:

ndhA

Encoded on

Plastid; Chloroplast

Organism

Chlorokybus atmophyticus (Soil alga)

Taxonomic identifier

3144 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Chlorokybophyceae › Chlorokybales › Chlorokybaceae › Chlorokybus

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity.
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01350
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the complex I subunit 1 family.

Ontologies

Keywords
Cellular component	Chloroplast Membrane Plastid Thylakoid
Domain	Transmembrane
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: HAMAP
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic HAMAP MF_01350		PRO_0000298868
Regions
	Transmembrane	29 – 49	21	Potential
	Transmembrane	96 – 116	21	Potential
	Transmembrane	128 – 148	21	Potential
	Transmembrane	166 – 186	21	Potential
	Transmembrane	204 – 224	21	Potential
	Transmembrane	255 – 277	23	Potential
	Transmembrane	297 – 317	21	Potential
	Transmembrane	333 – 353	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q19V58-1 [UniParc]. Last modified February 20, 2007. Version 2. Checksum: FAFCB98AE375483E	FASTA	360	39,433
	10 20 30 40 50 60 MLLIIDLQTA FINWFVGLGV SKDISAALWI PLPILVVIVG ATIGVLVIVW LERKISAGVQ 70 80 90 100 110 120 QRIGPEFAGP LGVLQPLADG LKLVFKEDII PSKADIWLFT LGPALVVIPV FLAYLVVPFG 130 140 150 160 170 180 HDLVVADISL GVFFWIAISS IAPIGLLMSG YGSNNKYSFL GGLRAAAQAI SYEIPLSLCV 190 200 210 220 230 240 LAICLLSNSL STVEIVEQQS AYGILGWNVW RQPIGFVSFL IAALAECERL PFDLPEAEEE 250 260 270 280 290 300 LVAGYQTEYS GMKFGLFYVG SYVNLLLSSL FATILYLGGW TSPITFSIPF QTSEIEIFAA 310 320 330 340 350 360 FLGIGMTLLK AYLFIFLSIL TRWTLPRVRI DQLLDLGWKF LLPISLGNLL LTASLRLAFY

References

[1]

"A clade uniting the green algae Mesostigma viride and Chlorokybus atmophyticus represents the deepest branch of the Streptophyta in chloroplast genome-based phylogenies." Lemieux C., Otis C., Turmel M. BMC Biol. 5:2-2(2007) [PubMed: 17222354] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SAG 48.80.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ422812 Genomic DNA. Translation: ABD62189.2.
RefSeq	YP_001019162.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4783215.
Family and domain databases
HAMAP	MF_01350. [Tree]
InterPro	IPR001694. NADH_UbQ_OxRdtase_su1. IPR018086. NADH_UbQ_OxRdtase_su1_CS. [Graphical view]
PANTHER	PTHR11432. Resp_NADH_DH_1. 1 hit.
Pfam	PF00146. NADHdh. 1 hit. [Graphical view]
PROSITE	PS00667. COMPLEX1_ND1_1. 1 hit. PS00668. COMPLEX1_ND1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NU1C_CHLAT

Accession

Primary (citable) accession number: Q19V58

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 21, 2007
Last sequence update:	February 20, 2007
Last modified:	June 16, 2009
This is version 21 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)