Q19R17 (Q19R17_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
T calcium channel alpha 1G subunit variant 25 EMBL ABF69901.1

Gene names

Name:

CACNA1G EMBL ABF69901.1

Organism

Homo sapiens (Human) EMBL ABF69901.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	2243 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378
Molecular function	Ionic channel RuleBase RU003378
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	voltage-gated calcium channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q19R17 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 74FA50071A5F9FBD	FASTA	2,243	248,529
	10 20 30 40 50 60 MDEEEDGAGA EESGQPRSFM RLNDLSGAGG RPGPGSAEKD PGSADSEAEG LPYPALAPVV 70 80 90 100 110 120 FFYLSQDSRP RSWCLRTVCN PWFERISMLV ILLNCVTLGM FRPCEDIACD SQRCRILQAF 130 140 150 160 170 180 DDFIFAFFAV EMVVKMVALG IFGKKCYLGD TWNRLDFFIV IAGMLEYSLD LQNVSFSAVR 190 200 210 220 230 240 TVRVLRPLRA INRVPSMRIL VTLLLDTLPM LGNVLLLCFF VFFIFGIVGV QLWAGLLRNR 250 260 270 280 290 300 CFLPENFSLP LSVDLERYYQ TENEDESPFI CSQPRENGMR SCRSVPTLRG DGGGGPPCGL 310 320 330 340 350 360 DYEAYNSSSN TTCVNWNQYY TNCSAGEHNP FKGAINFDNI GYAWIAIFQV ITLEGWVDIM 370 380 390 400 410 420 YFVMDAHSFY NFIYFILLII VGSFFMINLC LVVIATQFSE TKQRESQLMR EQRVRFLSNA 430 440 450 460 470 480 STLASFSEPG SCYEELLKYL VYILRKAARR LAQVSRAAGV RVGLLSSPAP LGGQETQPSS 490 500 510 520 530 540 SCSRSHRRLS VHHLVHHHHH HHHHYHLGNG TLRAPRASPE IQDRDANGSR RLMLPPPSTP 550 560 570 580 590 600 ALSGAPPGGA ESVHSFYHAD CHLEPVRCQA PPPRSPSEAS GRTVGSGKVY PTVHTSPPPE 610 620 630 640 650 660 TLKEKALVEV AASSGPPTLT SLNIPPGPYS SMHKLLETQS TGACQSSCKI SSPCLKADSG 670 680 690 700 710 720 ACGPDSCPYC ARAGAGEVEL ADREMPDSDS EAVYEFTQDA QHSDLRDPHS RRQRSLGPDA 730 740 750 760 770 780 EPSSVLAFWR LICDTFRKIV DSKYFGRGIM IAILVNTLSM GIEYHEQPEE LTNALEISNI 790 800 810 820 830 840 VFTSLFALEM LLKLLVYGPF GYIKNPYNIF DGVIVVISVW EIVGQQGGGL SVLRTFRLMR 850 860 870 880 890 900 VLKLVRFLPA LQRQLVVLMK TMDNVATFCM LLMLFIFIFS ILGMHLFGCK FASERDGDTL 910 920 930 940 950 960 PDRKNFDSLL WAIVTVFQIL TQEDWNKVLY NGMASTSSWA ALYFIALMTF GNYVLFNLLV 970 980 990 1000 1010 1020 AILVEGFQAE GDANKSESEP DFFSPSLDGD GDRKKCLALV SLGEHPELRK SLLPPLIIHT 1030 1040 1050 1060 1070 1080 AATPMSLPKS TSTGLGEALG PASRRTSSSG SAEPGAAHEM KSPPSARSSP HSPWSAASSW 1090 1100 1110 1120 1130 1140 TSRRSSRNSL GRAPSLKRRS PSGERRSLLS GEGQESQDEE ESSEEERASP AGSDHRHRGS 1150 1160 1170 1180 1190 1200 LEREAKSSFD LPDTLQVPGL HRTASGRGSA SEHQDCNGKS ASGRLARALR PDDPPLDGDD 1210 1220 1230 1240 1250 1260 ADDEGNLSKG ERVRAWIRAR LPACCLERDS WSAYIFPPQS RFRLLCHRII THKMFDHVVL 1270 1280 1290 1300 1310 1320 VIIFLNCITI AMERPKIDPH SAERIFLTLS NYIFTAVFLA EMTVKVVALG WCFGEQAYLR 1330 1340 1350 1360 1370 1380 SSWNVLDGLL VLISVIDILV SMVSDSGTKI LGMLRVLRLL RTLRPLRVIS RAQGLKLVVE 1390 1400 1410 1420 1430 1440 TLMSSLKPIG NIVVICCAFF IIFGILGVQL FKGKFFVCQG EDTRNITNKS DCAEASYRWV 1450 1460 1470 1480 1490 1500 RHKYNFDNLG QALMSLFVLA SKDGWVDIMY DGLDAVGVDQ QPIMNHNPWM LLYFISFLLI 1510 1520 1530 1540 1550 1560 VAFFVLNMFV GVVVENFHKC RQHQEEEEAR RREEKRLRRL EKKRRKAQCK PYYSDYSRFR 1570 1580 1590 1600 1610 1620 LLVHHLCTSH YLDLFITGVI GLNVVTMAME HYQQPQILDE ALKICNYIFT VIFVLESVFK 1630 1640 1650 1660 1670 1680 LVAFGFRRFF QDRWNQLDLA IVLLSIMGIT LEEIEVNASL PINPTIIRIM RVLRIARVLK 1690 1700 1710 1720 1730 1740 LLKMAVGMRA LLDTVMQALP QVGNLGLLFM LLFFIFAALG VELFGDLECD ETHPCEGLGR 1750 1760 1770 1780 1790 1800 HATFRNFGMA FLTLFRVSTG DNWNGIMKDT LRDCDQESTC YNTVISPIYF VSFVLTAQFV 1810 1820 1830 1840 1850 1860 LVNVVIAVLM KHLEESNKEA KEEAELEAEL ELEMKTLSPQ PHSPLGSPFL WPGVEGPDSP 1870 1880 1890 1900 1910 1920 DSPKPGALHP AAHARSASHF SLEHPTMQPH PTELPGPDLL TVRKSGVSRT HSLPNDSYMC 1930 1940 1950 1960 1970 1980 RHGSTAEGPL GHRGWGLPKA QSGSVLSVHS QPADTSYILQ LPKDAPHLLQ PHSAPTWGTI 1990 2000 2010 2020 2030 2040 PKLPPPGRSP LAQRPLRRQA AIRTDSLDVQ GLGSREDLLA EVSGPSPPLA RAYSFWGQSS 2050 2060 2070 2080 2090 2100 TQAQQHSRSH SKISKHMTPP APCPGPEPNW GKGPPETRSS LELDTELSWI SGDLLPPGGQ 2110 2120 2130 2140 2150 2160 EEPPSPRDLK KCYSVEAQSC QRRPTSWLDE QRRHSIAVSC LDSGSQPHLG TDPSNLGGQP 2170 2180 2190 2200 2210 2220 LGGPGSRPKK KLSPPSITID PPESQGPRTP PSPGICLRRR APSSDSKDPL ASGPPDSMAA 2230 2240 SPSPKKDVLS LSGLSSDPAD LDP

References

[1]	"Profiling the Array of Cav3.1 Variants from the Human T-type Calcium Channel Gene CACNA1G: Alternative Structures, Developmental Expression, and Biophysical Variations." Emerick M.C., Stein R., Kunze R., McNulty M.M., Regan M.R., Hanck D.A., Agnew W.S. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ494450 mRNA. Translation: ABF69901.1.
IPI	IPI00219391.
RefSeq	NP_938202.1. NM_198388.1.
UniGene	Hs.591169.
3D structure databases
ProteinModelPortal	Q19R17.
ModBase	Search...
Protein-protein interaction databases
STRING	Q19R17.
Proteomic databases
PRIDE	Q19R17.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8913.
KEGG	hsa:8913.
UCSC	uc002irn.1. human.
Organism-specific databases
CTD	8913.
Phylogenomic databases
GeneTree	ENSGT00560000076834.
HOVERGEN	HBG050764.
Gene expression databases
ArrayExpress	Q19R17.
Bgee	Q19R17.
Family and domain databases
InterPro	IPR005821. Ion_trans. IPR005445. VDCC_T_a1su. [Graphical view]
KO	K04854.
Pfam	PF00520. Ion_trans. 4 hits. [Graphical view]
PRINTS	PR01629. TVDCCALPHA1.
ProtoNet	Search...
Other
NextBio	33500.

Entry information

Entry name

Q19R17_HUMAN

Accession

Primary (citable) accession number: Q19R17

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	November 16, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.