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Unreviewed, UniProtKB/TrEMBL Q19QZ7 (Q19QZ7_HUMAN)

Last modified January 19, 2010. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    T calcium channel alpha 1G subunit variant 223 EMBL ABF69921.1
Gene names
Name: CACNA1G EMBL ABF69921.1
OrganismHomo sapiens (Human) EMBL ABF69921.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length2366 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity RuleBase RU003808V0.

Sequence similarities

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]

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Sequences

Sequence LengthMass (Da)Tools
Q19QZ7-1 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 2CBDED941FB8B793

FASTA2,366261,584
        10         20         30         40         50         60 
MDEEEDGAGA EESGQPRSFM RLNDLSGAGG RPGPGSAEKD PGSADSEAEG LPYPALAPVV 

        70         80         90        100        110        120 
FFYLSQDSRP RSWCLRTVCN PWFERISMLV ILLNCVTLGM FRPCEDIACD SQRCRILQAF 

       130        140        150        160        170        180 
DDFIFAFFAV EMVVKMVALG IFGKKCYLGD TWNRLDFFIV IAGMLEYSLD LQNVSFSAVR 

       190        200        210        220        230        240 
TVRVLRPLRA INRVPSMRIL VTLLLDTLPM LGNVLLLCFF VFFIFGIVGV QLWAGLLRNR 

       250        260        270        280        290        300 
CFLPENFSLP LSVDLERYYQ TENEDESPFI CSQPRENGMR SCRSVPTLRG DGGGGPPCGL 

       310        320        330        340        350        360 
DYEAYNSSSN TTCVNWNQYY TNCSAGEHNP FKGAINFDNI GYAWIAIFQV ITLEGWVDIM 

       370        380        390        400        410        420 
YFVMDAHSFY NFIYFILLII VGSFFMINLC LVVIATQFSE TKQRESQLMR EQRVRFLSNA 

       430        440        450        460        470        480 
STLASFSEPG SCYEELLKYL VYILRKAARR LAQVSRAAGV RVGLLSSPAP LGGQETQPSS 

       490        500        510        520        530        540 
SCSRSHRRLS VHHLVHHHHH HHHHYHLGNG TLRAPRASPE IQDRDANGSR RLMLPPPSTP 

       550        560        570        580        590        600 
ALSGAPPGGA ESVHSFYHAD CHLEPVRCQA PPPRSPSEAS GRTVGSGKVY PTVHTSPPPE 

       610        620        630        640        650        660 
TLKEKALVEV AASSGPPTLT SLNIPPGPYS SMHKLLETQS TGACQSSCKI SSPCLKADSG 

       670        680        690        700        710        720 
ACGPDSCPYC ARAGAGEVEL ADREMPDSDS EAVYEFTQDA QHSDLRDPHS RRQRSLGPDA 

       730        740        750        760        770        780 
EPSSVLAFWR LICDTFRKIV DSKYFGRGIM IAILVNTLSM GIEYHEQPEE LTNALEISNI 

       790        800        810        820        830        840 
VFTSLFALEM LLKLLVYGPF GYIKNPYNIF DGVIVVISVW EIVGQQGGGL SVLRTFRLMR 

       850        860        870        880        890        900 
VLKLVRFLPA LQRQLVVLMK TMDNVATFCM LLMLFIFIFS ILGMHLFGCK FASERDGDTL 

       910        920        930        940        950        960 
PDRKNFDSLL WAIVTVFQIL TQEDWNKVLY NGMASTSSWA ALYFIALMTF GNYVLFNLLV 

       970        980        990       1000       1010       1020 
AILVEGFQAE EISKREDASG QLSCIQLPVD SQGGDANKSE SEPDFFSPSL DGDGDRKKCL 

      1030       1040       1050       1060       1070       1080 
ALVSLGEHPE LRKSLLPPLI IHTAATPMSL PKSTSTGLGE ALGPASRRTS SSGSAEPGAA 

      1090       1100       1110       1120       1130       1140 
HEMKSPPSAR SSPHSPWSAA SSWTSRRSSR NSLGRAPSLK RRSPSGERRS LLSGEGQESQ 

      1150       1160       1170       1180       1190       1200 
DEEESSEEER ASPAGSDHRH RGSLEREAKS SFDLPDTLQV PGLHRTASGR GSASEHQDCN 

      1210       1220       1230       1240       1250       1260 
GKSASGRLAR ALRPDDPPLD GDDADDEGNL SKGERVRAWI RARLPACCLE RDSWSAYIFP 

      1270       1280       1290       1300       1310       1320 
PQSRFRLLCH RIITHKMFDH VVLVIIFLNC ITIAMERPKI DPHSAERIFL TLSNYIFTAV 

      1330       1340       1350       1360       1370       1380 
FLAEMTVKVV ALGWCFGEQA YLRSSWNVLD GLLVLISVID ILVSMVSDSG TKILGMLRVL 

      1390       1400       1410       1420       1430       1440 
RLLRTLRPLR VISRAQGLKL VVETLMSSLK PIGNIVVICC AFFIIFGILG VQLFKGKFFV 

      1450       1460       1470       1480       1490       1500 
CQGEDTRNIT NKSDCAEASY RWVRHKYNFD NLGQALMSLF VLASKDGWVD IMYDGLDAVG 

      1510       1520       1530       1540       1550       1560 
VDQQPIMNHN PWMLLYFISF LLIVAFFVLN MFVGVVVENF HKCRQHQEEE EARRREEKRL 

      1570       1580       1590       1600       1610       1620 
RRLEKKRRSK EKQMAEAQCK PYYSDYSRFR LLVHHLCTSH YLDLFITGVI GLNVVTMAME 

      1630       1640       1650       1660       1670       1680 
HYQQPQILDE ALKICNYIFT VIFVLESVFK LVAFGFRRFF QDRWNQLDLA IVLLSIMGIT 

      1690       1700       1710       1720       1730       1740 
LEEIEVNASL PINPTIIRIM RVLRIARVLK LLKMAVGMRA LLDTVMQALP QVGNLGLLFM 

      1750       1760       1770       1780       1790       1800 
LLFFIFAALG VELFGDLECD ETHPCEGLGR HATFRNFGMA FLTLFRVSTG DNWNGIMKDT 

      1810       1820       1830       1840       1850       1860 
LRDCDQESTC YNTVISPIYF VSFVLTAQFV LVNVVIAVLM KHLEESNKEA KEEAELEAEL 

      1870       1880       1890       1900       1910       1920 
ELEMKTLSPQ PHSPLGSPFL WPGVEGPDSP DSPKPGALHP AAHARSASHF SLEHPTDRQL 

      1930       1940       1950       1960       1970       1980 
FDTISLLIQG SLEWELKLMD ELAGPGGQPS AFPSAPSLGG SDPQIPLAEM EALSLTSEIV 

      1990       2000       2010       2020       2030       2040 
SEPSCSLALT DDSLPDDMHT LLLSALESNM QPHPTELPGP DLLTVRKSGV SRTHSLPNDS 

      2050       2060       2070       2080       2090       2100 
YMCRHGSTAE GPLGHRGWGL PKAQSGSVLS VHSQPADTSY ILQLPKDAPH LLQPHSAPTW 

      2110       2120       2130       2140       2150       2160 
GTIPKLPPPG RSPLAQRPLR RQAAIRTDSL DVQGLGSRED LLAEVSGPSP PLARAYSFWG 

      2170       2180       2190       2200       2210       2220 
QSSTQAQQHS RSHSKISKHM TPPAPCPGPE PNWGKGPPET RSSLELDTEL SWISGDLLPP 

      2230       2240       2250       2260       2270       2280 
GGQEEPPSPR DLKKCYSVEA QSCQRRPTSW LDEQRRHSIA VSCLDSGSQP HLGTDPSNLG 

      2290       2300       2310       2320       2330       2340 
GQPLGGPGSR PKKKLSPPSI TIDPPESQGP RTPPSPGICL RRRAPSSDSK DPLASGPPDS 

      2350       2360 
MAASPSPKKD VLSLSGLSSD PADLDP

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References

[1]"Profiling the Array of Cav3.1 Variants from the Human T-type Calcium Channel Gene CACNA1G: Alternative Structures, Developmental Expression, and Biophysical Variations."
Emerick M.C., Stein R., Kunze R., McNulty M.M., Regan M.R., Hanck D.A., Agnew W.S.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DQ494470 mRNA. Translation: ABF69921.1.
IPIIPI00394739.
UniGeneHs.591169

3D structure databases

SMRQ19QZ7. Positions 737-969, 1271-1543.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ19QZ7.

Genome annotation databases

EnsemblENST00000359106; ENSP00000352011; ENSG00000006283; Homo sapiens. [Genome view]
UCSCuc002iru.1. human.

Organism-specific databases

HGNCHGNC:1394. CACNA1G.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ19QZ7.

Gene expression databases

ArrayExpressQ19QZ7.
BgeeQ19QZ7.

Family and domain databases

InterProIPR005821. Ion_trans.
IPR005445. VDCC_T_a1su.
IPR002077. VDCCAlpha1.
[Graphical view]
PANTHERPTHR10037:SF44. TVDCCAlpha1. 1 hit.
PfamPF00520. Ion_trans. 4 hits.
[Graphical view]
PRINTSPR00167. CACHANNEL.
PR01629. TVDCCALPHA1.
ProtoNetSearch...

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Entry information

Entry nameQ19QZ7_HUMAN
AccessionPrimary (citable) accession number: Q19QZ7
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: January 19, 2010
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information