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Protein
Submitted name:

CD25

Gene

IL2RA

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CD25Imported
Submitted name:
Interleukin-2 receptor subunit alpha precursorImported
Gene namesi
Name:IL2RAImported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei239 – 261HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501509704622 – 272Sequence analysisAdd BLAST251

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 67PROSITE-ProRule annotation
Disulfide bondi125 ↔ 168PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000038209

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 84SushiInterPro annotationAdd BLAST63
Domaini123 – 186SushiInterPro annotationAdd BLAST64

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J24B Eukaryota
ENOG41116U7 LUCA
GeneTreeiENSGT00390000018872
HOGENOMiHOG000113044
HOVERGENiHBG052109
KOiK05068
OMAiTILNCEC
OrthoDBiEOG091G0NHH
TreeFamiTF337408

Family and domain databases

CDDicd00033 CCP, 1 hit
InterProiView protein in InterPro
IPR015486 IL-2_rcpt_alpha
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PANTHERiPTHR10573 PTHR10573, 1 hit
SMARTiView protein in SMART
SM00032 CCP, 2 hits
SUPFAMiSSF57535 SSF57535, 2 hits
PROSITEiView protein in PROSITE
PS50923 SUSHI, 2 hits

Sequencei

Sequence statusi: Complete.

Q19LH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSQLLMWGL LTFIMVPCCQ AELCDDDPPR ITYATFKALA YKEGTMLNCE
60 70 80 90 100
CSRGFRRIKS GSPYMLCTGS SSHSSWENQC QCIRSSPRNT TKQVTPQPEQ
110 120 130 140 150
QEERKPTEIP NPMQQVDQPS LPGHCREPPQ WENEGTERIY HFVVGQTVHY
160 170 180 190 200
QCIQGYRALH RGPAESICKM THGKTRWTQP RLVCTKETEP SQFPGEEEPQ
210 220 230 240 250
ASPDSLLESE NSCLITTTDF QVQTEVAATM ETFILTTKYQ LAVACCVFLL
260 270
ISVLLLSGLT WQQRRRKSRR TI
Length:272
Mass (Da):31,019
Last modified:July 11, 2006 - v1
Checksum:i40A0A05661208EAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ520834 mRNA Translation: ABF67510.1
GAMQ01006999 mRNA Translation: JAB34852.1
RefSeqiNP_001244147.1, NM_001257218.1

Genome annotation databases

EnsembliENSCJAT00000074635; ENSCJAP00000064540; ENSCJAG00000041838
GeneIDi100412016
KEGGicjc:100412016

Similar proteinsi

Entry informationi

Entry nameiQ19LH5_CALJA
AccessioniPrimary (citable) accession number: Q19LH5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: June 20, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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