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Q19A41

- KLF14_MOUSE

UniProt

Q19A41 - KLF14_MOUSE

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Protein

Krueppel-like factor 14

Gene

Klf14

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri195 – 22430C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri225 – 25430C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri255 – 28228C2H2-type 3PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Krueppel-like factor 14
Gene namesi
Name:Klf14
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:3577024. Klf14.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 325325Krueppel-like factor 14PRO_0000294169Add
BLAST

Proteomic databases

PRIDEiQ19A41.

Expressioni

Gene expression databases

BgeeiQ19A41.
CleanExiMM_KLF14.
GenevestigatoriQ19A41.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099122.

Structurei

3D structure databases

ProteinModelPortaliQ19A41.
SMRiQ19A41. Positions 156-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 3 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri195 – 22430C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri225 – 25430C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri255 – 28228C2H2-type 3PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG5048.
GeneTreeiENSGT00760000118984.
HOGENOMiHOG000233575.
HOVERGENiHBG050746.
InParanoidiQ19A41.
KOiK09208.
OMAiKRHQCSF.
OrthoDBiEOG7FJH0Q.
TreeFamiTF351003.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q19A41-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAAVACLDY FAAECLVSMS TRAVLHRRAT DPEGASAAAV SEVGAVSRES
60 70 80 90 100
AGKGTGSRGV LWIPPVLQVP TPSPGEGDGA PHLLAASALA DLSCGAREDF
110 120 130 140 150
REDSEEAPCA STSCFEPTWC SSPTGGSEPT QAFFEDELSD AESSCSDSAI
160 170 180 190 200
LDAPEASEEP DDSGEVPEGP PGARPAPSTG PTYRRRQITP ASKRHQCSFH
210 220 230 240 250
GCNKAYYKSS HLKSHQRTHT GERPFSCDWL DCDKKFTRSD ELARHYRTHT
260 270 280 290 300
GEKRFSCPLC PKQFSRSDHL TKHARRHPTY HPDMIEYRGR RRTPRPEPPP
310 320
PAMVESSGSD SSSSSGQETS FTACL
Length:325
Mass (Da):35,091
Last modified:July 11, 2006 - v1
Checksum:i5459637FFC0061BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ534758 mRNA. Translation: ABF82394.1.
CCDSiCCDS51744.1.
RefSeqiNP_001128565.1. NM_001135093.1.
UniGeneiMm.204671.

Genome annotation databases

EnsembliENSMUST00000101589; ENSMUSP00000099122; ENSMUSG00000073209.
GeneIDi619665.
KEGGimmu:619665.
UCSCiuc012ejp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ534758 mRNA. Translation: ABF82394.1 .
CCDSi CCDS51744.1.
RefSeqi NP_001128565.1. NM_001135093.1.
UniGenei Mm.204671.

3D structure databases

ProteinModelPortali Q19A41.
SMRi Q19A41. Positions 156-277.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000099122.

Proteomic databases

PRIDEi Q19A41.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000101589 ; ENSMUSP00000099122 ; ENSMUSG00000073209 .
GeneIDi 619665.
KEGGi mmu:619665.
UCSCi uc012ejp.1. mouse.

Organism-specific databases

CTDi 136259.
MGIi MGI:3577024. Klf14.

Phylogenomic databases

eggNOGi COG5048.
GeneTreei ENSGT00760000118984.
HOGENOMi HOG000233575.
HOVERGENi HBG050746.
InParanoidi Q19A41.
KOi K09208.
OMAi KRHQCSF.
OrthoDBi EOG7FJH0Q.
TreeFami TF351003.

Miscellaneous databases

NextBioi 414786.
PROi Q19A41.
SOURCEi Search...

Gene expression databases

Bgeei Q19A41.
CleanExi MM_KLF14.
Genevestigatori Q19A41.

Family and domain databases

Gene3Di 3.30.160.60. 3 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 3 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The centre for applied genomics genome annotation project."
    Parker-Katiraee L., Scherer S.W.
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiKLF14_MOUSE
AccessioniPrimary (citable) accession number: Q19A41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 11, 2006
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3