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Q19A41

- KLF14_MOUSE

UniProt

Q19A41 - KLF14_MOUSE

Protein

Krueppel-like factor 14

Gene

Klf14

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri195 – 22430C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri225 – 25430C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri255 – 28228C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Krueppel-like factor 14
    Gene namesi
    Name:Klf14
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 6

    Organism-specific databases

    MGIiMGI:3577024. Klf14.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 325325Krueppel-like factor 14PRO_0000294169Add
    BLAST

    Proteomic databases

    PRIDEiQ19A41.

    Expressioni

    Gene expression databases

    BgeeiQ19A41.
    CleanExiMM_KLF14.
    GenevestigatoriQ19A41.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000099122.

    Structurei

    3D structure databases

    ProteinModelPortaliQ19A41.
    SMRiQ19A41. Positions 156-323.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 3 C2H2-type zinc fingers.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri195 – 22430C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri225 – 25430C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri255 – 28228C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG5048.
    GeneTreeiENSGT00750000117414.
    HOGENOMiHOG000233575.
    HOVERGENiHBG050746.
    InParanoidiQ19A41.
    KOiK09208.
    OMAiKRHQCSF.
    OrthoDBiEOG7FJH0Q.
    TreeFamiTF351003.

    Family and domain databases

    Gene3Di3.30.160.60. 3 hits.
    InterProiIPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    SMARTiSM00355. ZnF_C2H2. 3 hits.
    [Graphical view]
    PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
    PS50157. ZINC_FINGER_C2H2_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q19A41-1 [UniParc]FASTAAdd to Basket

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    MSAAVACLDY FAAECLVSMS TRAVLHRRAT DPEGASAAAV SEVGAVSRES    50
    AGKGTGSRGV LWIPPVLQVP TPSPGEGDGA PHLLAASALA DLSCGAREDF 100
    REDSEEAPCA STSCFEPTWC SSPTGGSEPT QAFFEDELSD AESSCSDSAI 150
    LDAPEASEEP DDSGEVPEGP PGARPAPSTG PTYRRRQITP ASKRHQCSFH 200
    GCNKAYYKSS HLKSHQRTHT GERPFSCDWL DCDKKFTRSD ELARHYRTHT 250
    GEKRFSCPLC PKQFSRSDHL TKHARRHPTY HPDMIEYRGR RRTPRPEPPP 300
    PAMVESSGSD SSSSSGQETS FTACL 325
    Length:325
    Mass (Da):35,091
    Last modified:July 11, 2006 - v1
    Checksum:i5459637FFC0061BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ534758 mRNA. Translation: ABF82394.1.
    CCDSiCCDS51744.1.
    RefSeqiNP_001128565.1. NM_001135093.1.
    UniGeneiMm.204671.

    Genome annotation databases

    EnsembliENSMUST00000101589; ENSMUSP00000099122; ENSMUSG00000073209.
    GeneIDi619665.
    KEGGimmu:619665.
    UCSCiuc012ejp.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ534758 mRNA. Translation: ABF82394.1 .
    CCDSi CCDS51744.1.
    RefSeqi NP_001128565.1. NM_001135093.1.
    UniGenei Mm.204671.

    3D structure databases

    ProteinModelPortali Q19A41.
    SMRi Q19A41. Positions 156-323.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000099122.

    Proteomic databases

    PRIDEi Q19A41.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000101589 ; ENSMUSP00000099122 ; ENSMUSG00000073209 .
    GeneIDi 619665.
    KEGGi mmu:619665.
    UCSCi uc012ejp.1. mouse.

    Organism-specific databases

    CTDi 136259.
    MGIi MGI:3577024. Klf14.

    Phylogenomic databases

    eggNOGi COG5048.
    GeneTreei ENSGT00750000117414.
    HOGENOMi HOG000233575.
    HOVERGENi HBG050746.
    InParanoidi Q19A41.
    KOi K09208.
    OMAi KRHQCSF.
    OrthoDBi EOG7FJH0Q.
    TreeFami TF351003.

    Miscellaneous databases

    NextBioi 414786.
    PROi Q19A41.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q19A41.
    CleanExi MM_KLF14.
    Genevestigatori Q19A41.

    Family and domain databases

    Gene3Di 3.30.160.60. 3 hits.
    InterProi IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    SMARTi SM00355. ZnF_C2H2. 3 hits.
    [Graphical view ]
    PROSITEi PS00028. ZINC_FINGER_C2H2_1. 3 hits.
    PS50157. ZINC_FINGER_C2H2_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The centre for applied genomics genome annotation project."
      Parker-Katiraee L., Scherer S.W.
      Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiKLF14_MOUSE
    AccessioniPrimary (citable) accession number: Q19A41
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3