Reviewed,
UniProtKB/Swiss-Prot Q19A30 (AL9A1_ORYLA)
Last modified
October 13, 2009.
Version 27.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Aldehyde dehydrogenase family 9 member A1 EC=1.2.1.3 | ||||
| Gene names |
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| Organism | Oryzias latipes (Medaka fish) (Japanese ricefish) | ||||
| Taxonomic identifier | 8090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Atherinomorpha › Beloniformes › Adrianichthyidae › Oryziinae › Oryzias |
Protein attributes
| Sequence length | 505 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | An aldehyde + NAD+ + H2O = an acid + NADH. |
| Subunit structure | Homotetramer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Tissue specificity | Constitutively expressed in all organs tested: brain, eye, gill, GI, heart, liver, kidney, muscle, skin, testis and ovary. Ref.1 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Ethanol attenuates Aldh9 mRNA expression in Japanese medaka (Oryzias latipes) embryogenesis." Wang X., Zhu S., Khan I.A., Dasmahapatra A.K. Comp. Biochem. Physiol. 146B:357-363(2007) [PubMed: 17236798] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY. |
Cross-references
Sequence databases | |
|---|---|
| DQ535181 mRNA. Translation: ABF83193.1. | |
| RefSeq | NP_001098318.1. |
| UniGene | Ola.6101 |
3D structure databases | |
| SMR | Q19A30. Positions 6-505. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q19A30. |
Genome annotation databases | |
| Ensembl | ENSORLT00000017773; ENSORLP00000017772; ENSORLG00000014167; Oryzias latipes. [Genome view] |
| GeneID | 100049493. |
Organism-specific databases | |
| CTD | 100049493. |
Phylogenomic databases | |
| HOVERGEN | Q19A30. |
Enzyme and pathway databases | |
| BRENDA | 1.2.1.3. 19130. |
Family and domain databases | |
| InterPro | IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. [Graphical view] |
| Gene3D | G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| PANTHER | PTHR11699. Aldehyde_dehyd. 1 hit. |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AL9A1_ORYLA | ||||||||
| Accession | Primary (citable) accession number: Q19A30 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||

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