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Protein

Tetraspanin

Gene

tsp-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-114608. Platelet degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
TetraspaninUniRule annotation
Gene namesi
Name:tsp-8Imported
ORF Names:CELE_F33C8.3Imported, F33C8.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF33C8.3; CE05798; WBGene00006634; tsp-8.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 35HelicalUniRule annotationAdd BLAST24
Transmembranei55 – 79HelicalUniRule annotationAdd BLAST25
Transmembranei86 – 108HelicalUniRule annotationAdd BLAST23
Transmembranei251 – 276HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ19983.
PaxDbiQ19983.
PeptideAtlasiQ19983.

Expressioni

Gene expression databases

BgeeiWBGene00006634.

Interactioni

Protein-protein interaction databases

DIPiDIP-27103N.
MINTiMINT-1062250.
STRINGi6239.F33C8.3.

Structurei

3D structure databases

ProteinModelPortaliQ19983.
SMRiQ19983.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3882. Eukaryota.
ENOG4111IRY. LUCA.
GeneTreeiENSGT00880000137858.
HOGENOMiHOG000018336.
InParanoidiQ19983.
OMAiNQCALAF.
OrthoDBiEOG091G0HB7.
PhylomeDBiQ19983.

Family and domain databases

Gene3Di1.10.1450.10. 1 hit.
InterProiView protein in InterPro
IPR000301. Tetraspanin.
IPR018499. Tetraspanin/Peripherin.
IPR008952. Tetraspanin_EC2_sf.
PfamiView protein in Pfam
PF00335. Tetraspannin. 1 hit.
PIRSFiPIRSF002419. Tetraspanin. 1 hit.
PRINTSiPR00259. TMFOUR.
SUPFAMiSSF48652. SSF48652. 2 hits.

Sequencei

Sequence statusi: Complete.

Q19983-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSCVNALRI VTFLFNFAFW LSGVVVFGLG IWLLFDPAAS DFFALHSTHP
60 70 80 90 100
GAFRYVGWFL VGAGAIIILV GYFGCIGAWK MNQCALAFFC CILILAFFLE
110 120 130 140 150
LAAAVTLFHK QEHIKHYVES SMYDTIRNRY SSETAFKDAF DTVQEKFECC
160 170 180 190 200
GVKTYTDWLS ARWDAEPSTQ LEVNEEDAGR IEHGIGAFGG NKGTGYGRVP
210 220 230 240 250
SSCCNEHGKL SYPNNCGRSF SQAPLNTYAQ FINTRGCADA VYESVSSSLS
260 270 280
LIVGVCVVLC IVQLLGIVLS MTLCCCKGNS KK
Length:282
Mass (Da):30,943
Last modified:November 1, 1996 - v1
Checksum:i400215C630281FD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA93655.1.
PIRiT21696.
RefSeqiNP_510445.1. NM_078044.5.
UniGeneiCel.245.

Genome annotation databases

EnsemblMetazoaiF33C8.3; F33C8.3; WBGene00006634.
GeneIDi181567.
KEGGicel:CELE_F33C8.3.
UCSCiF33C8.3. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ19983_CAEEL
AccessioniPrimary (citable) accession number: Q19983
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported