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Protein

Tetraspanin

Gene

tsp-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
TetraspaninUniRule annotation
Gene namesi
Name:tsp-8Imported
ORF Names:CELE_F33C8.3Imported, F33C8.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi

Organism-specific databases

WormBaseiF33C8.3 ; CE05798 ; WBGene00006634 ; tsp-8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 35HelicalUniRule annotationAdd BLAST24
Transmembranei55 – 79HelicalUniRule annotationAdd BLAST25
Transmembranei86 – 108HelicalUniRule annotationAdd BLAST23
Transmembranei251 – 276HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ19983
PaxDbiQ19983
PeptideAtlasiQ19983

Expressioni

Gene expression databases

BgeeiWBGene00006634

Interactioni

Protein-protein interaction databases

DIPiDIP-27103N
STRINGi6239.F33C8.3

Structurei

3D structure databases

ProteinModelPortaliQ19983
SMRiQ19983
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137858
HOGENOMiHOG000018336
InParanoidiQ19983
OMAiNQCALAF
OrthoDBiEOG091G0HB7
PhylomeDBiQ19983

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 2 hits

Sequencei

Sequence statusi: Complete.

Q19983-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSCVNALRI VTFLFNFAFW LSGVVVFGLG IWLLFDPAAS DFFALHSTHP
60 70 80 90 100
GAFRYVGWFL VGAGAIIILV GYFGCIGAWK MNQCALAFFC CILILAFFLE
110 120 130 140 150
LAAAVTLFHK QEHIKHYVES SMYDTIRNRY SSETAFKDAF DTVQEKFECC
160 170 180 190 200
GVKTYTDWLS ARWDAEPSTQ LEVNEEDAGR IEHGIGAFGG NKGTGYGRVP
210 220 230 240 250
SSCCNEHGKL SYPNNCGRSF SQAPLNTYAQ FINTRGCADA VYESVSSSLS
260 270 280
LIVGVCVVLC IVQLLGIVLS MTLCCCKGNS KK
Length:282
Mass (Da):30,943
Last modified:November 1, 1996 - v1
Checksum:i400215C630281FD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CAA93655.1
PIRiT21696
RefSeqiNP_510445.1, NM_078044.5
UniGeneiCel.245

Genome annotation databases

EnsemblMetazoaiF33C8.3; F33C8.3; WBGene00006634
GeneIDi181567
KEGGicel:CELE_F33C8.3
UCSCiF33C8.3 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ19983_CAEEL
AccessioniPrimary (citable) accession number: Q19983
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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