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Protein
Submitted name:

Heavy chain, Unconventional Myosin

Gene

hum-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ19901.

Names & Taxonomyi

Protein namesi
Submitted name:
Heavy chain, Unconventional MyosinImported
Gene namesi
Name:hum-1Imported
ORF Names:CELE_F29D10.4Imported, F29D10.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF29D10.4; CE05763; WBGene00002035; hum-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ19901.
PaxDbiQ19901.
PRIDEiQ19901.

Expressioni

Gene expression databases

ExpressionAtlasiQ19901. baseline.

Interactioni

Protein-protein interaction databases

DIPiDIP-24485N.
IntActiQ19901. 8 interactions.
MINTiMINT-1088644.
STRINGi6239.F29D10.4.

Structurei

3D structure databases

ProteinModelPortaliQ19901.
SMRiQ19901. Positions 15-739, 1041-1099.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 690677Myosin motorInterPro annotationAdd
BLAST
Domaini728 – 922195TH1 (class I myosin tail homology)InterPro annotationAdd
BLAST
Domaini1044 – 110057SH3InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation
Contains 1 SH3 domain.UniRule annotation
Contains TH1 (class I myosin tail homology) domain.SAAS annotation
Contains myosin motor domain.SAAS annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0164. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00840000129861.
HOGENOMiHOG000260265.
InParanoidiQ19901.
KOiK10356.
OMAiKENWGFL.
PhylomeDBiQ19901.

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR025660. Pept_his_AS.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q19901-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFHWQSKVN VQHVGVDDMV LLPKLTEQSI VENLKKRLQA NSIFTYIGPV
60 70 80 90 100
LISVNPFKQM PYFTEKEMLL YQGAAQYENA PHIYALADNM YRNMLIDNES
110 120 130 140 150
QCVIISGESG AGKTVNAKFI MNYISRISGG GQKVQHIKDV ILQSNPLLEA
160 170 180 190 200
FGNSATVRNW NSSRFGKYVE IVFSRGGEPI GGKLSNFLLE KSRVVHQNEG
210 220 230 240 250
DRNFHVFYQL CAGADKNLRS TFGIGELQYY NYLNMSGVFK ADDTDDGKEF
260 270 280 290 300
ESTLHAMKVV GVNDQDQLEV LRIVATVLHI GNITFTEENN FAAVSGKDYL
310 320 330 340 350
EYPAFLLGLT SADIEAKLTG RKMESKWGTQ KEEIDMKLNV EQASYTRDAW
360 370 380 390 400
VKAIYARLFD YLVKKVNDAM NITSQSTSDN FSVGILDIYG FEIFNNNGFE
410 420 430 440 450
QFCINFVNEK LQQIFIELTL KAEQEEYVRE GIKWTEIDYF DNKIVCDLIE
460 470 480 490 500
TKRPPGIMSL LDDTCAQNHG QREGVDRQLL TTLSKSFAGH PHFGPGSDSF
510 520 530 540 550
VIKHYAGDVT YNVDGFCDRN RDVLYPDLIL LMQKSSRPFI QALFPENVAA
560 570 580 590 600
SAGKRPTTFS TKIRTQANTL VESLMKCSPH YVRCIKPNET KRPNDWEESR
610 620 630 640 650
VKHQVEYLGL RENIRVRRAG FAYRRAFDKF AQRYAIVSPQ TWPCFQGDQQ
660 670 680 690 700
RACEIICDSV HMEKNQYQMG KTKIFVKNPE SLFLLEETRE RKFDGYARVI
710 720 730 740 750
QKAWRQFSAR KQHIKQKEQA ADLMYGKKER RRYSLNRNFV GDYIGLEHHP
760 770 780 790 800
TLQSLVGKRQ RVLFACTANK YDRKFRVTKL DLLLTVNHLT LIGKEKVKNG
810 820 830 840 850
PEKGKIVEVI KRQFDLPQIK SIGLSPYQDD FVILYLGNDD YSSLLETPFK
860 870 880 890 900
TEFCTALSKA YKERTNGTLH LDFRSSHVVS YKKMKFDFSD GKRTVQFGND
910 920 930 940 950
GTSSAEKTLK PNGKVLNVSI GTGLPNTTRP STERPQGGYT PRRDQLRTST
960 970 980 990 1000
RRTKQNNQSY GQNGQSQAMR APVPAHGMNN NYNQTPAPVS TNHQYSQEPA
1010 1020 1030 1040 1050
RIPVMGNVIN QLNNMNLSGN GNSPAGRGPP PARGPKPPPP AKPKLNPVVI
1060 1070 1080 1090 1100
AVYPYEAQDV DELSFEAGAE IELMNKDASG WWQGKVNNRV GLFPGNYVKE
Length:1,100
Mass (Da):124,886
Last modified:November 1, 1996 - v1
Checksum:i2CDB6F02EDEEDED9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00095.1.
PIRiT21544.
RefSeqiNP_492393.1. NM_059992.3.
UniGeneiCel.17027.

Genome annotation databases

EnsemblMetazoaiF29D10.4; F29D10.4; WBGene00002035.
GeneIDi172698.
KEGGicel:CELE_F29D10.4.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00095.1.
PIRiT21544.
RefSeqiNP_492393.1. NM_059992.3.
UniGeneiCel.17027.

3D structure databases

ProteinModelPortaliQ19901.
SMRiQ19901. Positions 15-739, 1041-1099.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-24485N.
IntActiQ19901. 8 interactions.
MINTiMINT-1088644.
STRINGi6239.F29D10.4.

Proteomic databases

EPDiQ19901.
PaxDbiQ19901.
PRIDEiQ19901.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF29D10.4; F29D10.4; WBGene00002035.
GeneIDi172698.
KEGGicel:CELE_F29D10.4.

Organism-specific databases

CTDi172698.
WormBaseiF29D10.4; CE05763; WBGene00002035; hum-1.

Phylogenomic databases

eggNOGiKOG0164. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00840000129861.
HOGENOMiHOG000260265.
InParanoidiQ19901.
KOiK10356.
OMAiKENWGFL.
PhylomeDBiQ19901.

Enzyme and pathway databases

SignaLinkiQ19901.

Miscellaneous databases

NextBioi876635.

Gene expression databases

ExpressionAtlasiQ19901. baseline.

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR025660. Pept_his_AS.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ19901_CAEEL
AccessioniPrimary (citable) accession number: Q19901
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 136 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.