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Protein
Submitted name:

Heavy chain, Unconventional Myosin

Gene

hum-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi107 – 114ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ19901

Names & Taxonomyi

Protein namesi
Submitted name:
Heavy chain, Unconventional MyosinImported
Gene namesi
Name:hum-1Imported
ORF Names:CELE_F29D10.4Imported, F29D10.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF29D10.4 ; CE05763 ; WBGene00002035 ; hum-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiQ19901
PaxDbiQ19901
PeptideAtlasiQ19901

Expressioni

Gene expression databases

BgeeiWBGene00002035
ExpressionAtlasiQ19901 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-24485N
IntActiQ19901, 8 interactors
STRINGi6239.F29D10.4

Structurei

3D structure databases

ProteinModelPortaliQ19901
SMRiQ19901
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 690Myosin motorInterPro annotationAdd BLAST677
Domaini728 – 922TH1InterPro annotationAdd BLAST195
Domaini1044 – 1100SH3InterPro annotationAdd BLAST57

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni567 – 589Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0164 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00910000144051
HOGENOMiHOG000260265
InParanoidiQ19901
KOiK10356
OMAiKENWGPW
OrthoDBiEOG091G0136
PhylomeDBiQ19901

Family and domain databases

CDDicd01378 MYSc_Myo1, 1 hit
Gene3Di3.40.850.10, 3 hits
InterProiView protein in InterPro
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR010926 Myosin_TH1
IPR036072 MYSc_Myo1
IPR027417 P-loop_NTPase
IPR025660 Pept_his_AS
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF06017 Myosin_TH1, 1 hit
PF00018 SH3_1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51456 MYOSIN_MOTOR, 1 hit
PS50002 SH3, 1 hit
PS51757 TH1, 1 hit
PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequencei

Sequence statusi: Complete.

Q19901-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFHWQSKVN VQHVGVDDMV LLPKLTEQSI VENLKKRLQA NSIFTYIGPV
60 70 80 90 100
LISVNPFKQM PYFTEKEMLL YQGAAQYENA PHIYALADNM YRNMLIDNES
110 120 130 140 150
QCVIISGESG AGKTVNAKFI MNYISRISGG GQKVQHIKDV ILQSNPLLEA
160 170 180 190 200
FGNSATVRNW NSSRFGKYVE IVFSRGGEPI GGKLSNFLLE KSRVVHQNEG
210 220 230 240 250
DRNFHVFYQL CAGADKNLRS TFGIGELQYY NYLNMSGVFK ADDTDDGKEF
260 270 280 290 300
ESTLHAMKVV GVNDQDQLEV LRIVATVLHI GNITFTEENN FAAVSGKDYL
310 320 330 340 350
EYPAFLLGLT SADIEAKLTG RKMESKWGTQ KEEIDMKLNV EQASYTRDAW
360 370 380 390 400
VKAIYARLFD YLVKKVNDAM NITSQSTSDN FSVGILDIYG FEIFNNNGFE
410 420 430 440 450
QFCINFVNEK LQQIFIELTL KAEQEEYVRE GIKWTEIDYF DNKIVCDLIE
460 470 480 490 500
TKRPPGIMSL LDDTCAQNHG QREGVDRQLL TTLSKSFAGH PHFGPGSDSF
510 520 530 540 550
VIKHYAGDVT YNVDGFCDRN RDVLYPDLIL LMQKSSRPFI QALFPENVAA
560 570 580 590 600
SAGKRPTTFS TKIRTQANTL VESLMKCSPH YVRCIKPNET KRPNDWEESR
610 620 630 640 650
VKHQVEYLGL RENIRVRRAG FAYRRAFDKF AQRYAIVSPQ TWPCFQGDQQ
660 670 680 690 700
RACEIICDSV HMEKNQYQMG KTKIFVKNPE SLFLLEETRE RKFDGYARVI
710 720 730 740 750
QKAWRQFSAR KQHIKQKEQA ADLMYGKKER RRYSLNRNFV GDYIGLEHHP
760 770 780 790 800
TLQSLVGKRQ RVLFACTANK YDRKFRVTKL DLLLTVNHLT LIGKEKVKNG
810 820 830 840 850
PEKGKIVEVI KRQFDLPQIK SIGLSPYQDD FVILYLGNDD YSSLLETPFK
860 870 880 890 900
TEFCTALSKA YKERTNGTLH LDFRSSHVVS YKKMKFDFSD GKRTVQFGND
910 920 930 940 950
GTSSAEKTLK PNGKVLNVSI GTGLPNTTRP STERPQGGYT PRRDQLRTST
960 970 980 990 1000
RRTKQNNQSY GQNGQSQAMR APVPAHGMNN NYNQTPAPVS TNHQYSQEPA
1010 1020 1030 1040 1050
RIPVMGNVIN QLNNMNLSGN GNSPAGRGPP PARGPKPPPP AKPKLNPVVI
1060 1070 1080 1090 1100
AVYPYEAQDV DELSFEAGAE IELMNKDASG WWQGKVNNRV GLFPGNYVKE
Length:1,100
Mass (Da):124,886
Last modified:November 1, 1996 - v1
Checksum:i2CDB6F02EDEEDED9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB00095.1
PIRiT21544
RefSeqiNP_492393.1, NM_059992.3
UniGeneiCel.17027

Genome annotation databases

EnsemblMetazoaiF29D10.4; F29D10.4; WBGene00002035
GeneIDi172698
KEGGicel:CELE_F29D10.4

Similar proteinsi

Entry informationi

Entry nameiQ19901_CAEEL
AccessioniPrimary (citable) accession number: Q19901
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 155 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health