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Protein

60S ribosomal protein L26

Gene

rpl-26

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L26
Gene namesi
Name:rpl-26
ORF Names:F28C6.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF28C6.7a; CE03278; WBGene00004440; rpl-26.
F28C6.7b; CE20731; WBGene00004440; rpl-26.
F28C6.7c; CE32883; WBGene00004440; rpl-26.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001307951 – 14260S ribosomal protein L26Add BLAST142

Proteomic databases

EPDiQ19869.
PaxDbiQ19869.
PeptideAtlasiQ19869.
PRIDEiQ19869.

PTM databases

iPTMnetiQ19869.

Expressioni

Gene expression databases

BgeeiWBGene00004440.
ExpressionAtlasiQ19869. baseline.

Interactioni

Protein-protein interaction databases

BioGridi39707. 1 interactor.
STRINGi6239.F28C6.7a.2.

Structurei

3D structure databases

ProteinModelPortaliQ19869.
SMRiQ19869.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3401. Eukaryota.
COG0198. LUCA.
GeneTreeiENSGT00390000014165.
HOGENOMiHOG000216571.
InParanoidiQ19869.
KOiK02898.
OMAiVRIMRGD.
OrthoDBiEOG091G0TZX.
PhylomeDBiQ19869.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
HAMAPiMF_01326_A. Ribosomal_L24_A. 1 hit.
InterProiView protein in InterPro
IPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR005825. Ribosomal_L24/26_CS.
IPR005756. Ribosomal_L26/L24P_euk/arc.
IPR008991. Translation_prot_SH3-like.
PANTHERiPTHR11143. PTHR11143. 1 hit.
PfamiView protein in Pfam
PF00467. KOW. 1 hit.
PF16906. Ribosomal_L26. 1 hit.
SMARTiView protein in SMART
SM00739. KOW. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
TIGRFAMsiTIGR01080. rplX_A_E. 1 hit.
PROSITEiView protein in PROSITE
PS01108. RIBOSOMAL_L24. 1 hit.

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform a (identifier: Q19869-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKVNPFVSSD SGKSRKAHFN APSHERRRIM SAPLTKELRT KHGIRAIPIR
60 70 80 90 100
TDDEVVVMRG RHKGNTGRVL RCYRKKFVIH IDKITREKAN GSTVHIGIHP
110 120 130 140
SKVAITKLKL DKDRRALVER KAAGRSRVTG ILKGKHTDET VN
Note: No experimental confirmation available.
Length:142
Mass (Da):16,075
Last modified:November 1, 1997 - v1
Checksum:iB496362F0BFEC354
GO
Isoform b (identifier: Q19869-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     104-142: AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN → RFV

Note: No experimental confirmation available.
Show »
Length:106
Mass (Da):12,149
Checksum:iBFC2D533D71991EA
GO
Isoform c (identifier: Q19869-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     104-142: AITKLKLDKDRRALVERKAAGRSRVTGILKGKHTDETVN → RSLSPS

Note: No experimental confirmation available.
Show »
Length:109
Mass (Da):12,374
Checksum:i6255499A3EA533D7
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_020728104 – 142AITKL…DETVN → RFV in isoform b. CuratedAdd BLAST39
Alternative sequenceiVSP_020727104 – 142AITKL…DETVN → RSLSPS in isoform c. CuratedAdd BLAST39

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68315 Genomic DNA. Translation: CAA92674.1.
Z68315 Genomic DNA. Translation: CAA92678.1.
Z68315 Genomic DNA. Translation: CAD59149.1.
PIRiT21486.
T21490.
RefSeqiNP_495823.1. NM_063422.4. [Q19869-1]
NP_495824.1. NM_063423.6. [Q19869-2]
NP_871965.1. NM_182165.5. [Q19869-3]
UniGeneiCel.18248.

Genome annotation databases

EnsemblMetazoaiF28C6.7a.1; F28C6.7a.1; WBGene00004440. [Q19869-1]
F28C6.7a.2; F28C6.7a.2; WBGene00004440. [Q19869-1]
F28C6.7a.3; F28C6.7a.3; WBGene00004440. [Q19869-1]
GeneIDi174379.
KEGGicel:CELE_F28C6.7.
UCSCiF28C6.7a.1. c. elegans. [Q19869-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL26_CAEEL
AccessioniPrimary (citable) accession number: Q19869
Secondary accession number(s): Q8I121, Q9U3H7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 5, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families