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Protein
Submitted name:

NEPrilysin metallopeptidase family

Gene

nep-12

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Protein family/group databases

MEROPSiM13.A26.

Names & Taxonomyi

Protein namesi
Submitted name:
NEPrilysin metallopeptidase familyImported
Gene namesi
Name:nep-12Imported
ORF Names:CELE_F26G1.6Imported, F26G1.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF26G1.6; CE37363; WBGene00017842; nep-12.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 52HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ19831.

Expressioni

Gene expression databases

BgeeiWBGene00017842.

Structurei

3D structure databases

ProteinModelPortaliQ19831.
SMRiQ19831.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 504Peptidase_M13_NInterPro annotationAdd BLAST392
Domaini530 – 733Peptidase_M13InterPro annotationAdd BLAST204

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3624. Eukaryota.
COG3590. LUCA.
GeneTreeiENSGT00760000119162.
HOGENOMiHOG000021868.
InParanoidiQ19831.
KOiK01389.
OMAiYANTWCE.
OrthoDBiEOG091G021W.
PhylomeDBiQ19831.

Family and domain databases

CDDicd08662. M13. 1 hit.
Gene3Di3.40.390.10. 2 hits.
InterProiView protein in InterPro
IPR024079. MetalloPept_cat_dom.
IPR000718. Peptidase_M13.
IPR018497. Peptidase_M13_C.
IPR008753. Peptidase_M13_N.
PANTHERiPTHR11733. PTHR11733. 1 hit.
PfamiView protein in Pfam
PF01431. Peptidase_M13. 1 hit.
PF05649. Peptidase_M13_N. 1 hit.
PRINTSiPR00786. NEPRILYSIN.

Sequencei

Sequence statusi: Complete.

Q19831-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKKSKTVMI DYSITKILER NKKNARLAAV FAALFILTLL ISISFITIVA
60 70 80 90 100
ILSDGFSTLI SGSELCSNTE GDAYEVKNSN HVNYGSDNST CLTPECIRLA
110 120 130 140 150
ASYLNNMNRD ANPCEDFYEF ACGKYATRKV IAEHEKKVTV LSEMKKEMDR
160 170 180 190 200
HLKDILEKTS RENTTRSMKL AQIYFDSCMD EFSQDDLGVQ PLMSMISNLG
210 220 230 240 250
GWPLLTNARF DSIDFQWEVL AGHLALYGVD GIFRVFVHSS FDDSDKNVLM
260 270 280 290 300
FSPPKLFLEK KKFYREVPSS NVYLQYYRQY ILSLLSLLGV DMEDETGVIE
310 320 330 340 350
YQVDDIIDFE RRIANLTRIE LSRNHSSINN MITFGEFKRK YDKINWDAFF
360 370 380 390 400
NEEMRGNLGR MPDSLVINVV DVNYFDNLYS LIKSKPLSSI NNFLMWCLVS
410 420 430 440 450
NYDMYLPAKY RKPMLDFRQK MYGVSSDDPL WEVCVGEVRE NLAMPLSTEY
460 470 480 490 500
AQKFFTKKDK LVAEDMIRDL KKAMEQTLLN ADWIDESTRE AALMKLDAMG
510 520 530 540 550
HKIGDALSKL HRTPSLIDWA SPIIAVDAFH YFTGNEIIFP AGILQFPMFV
560 570 580 590 600
PDAPAFSNYG AIGMGIGHEI THGYDDLGAQ YDDKGNLRGW WHTETMTTFQ
610 620 630 640 650
KKKQCFVAQY GSKIEPQTGR KVDGKMTIGE NIADNGGLRV AFQAYQLRSD
660 670 680 690 700
REKETRRLPG LTDFSPNQLF FLAYANTWCE ALKPSAIDHI MDTDVHSLGM
710 720 730
FRVNVPLQNL PAFSKEFDCP IGSPMNPFEK CRIW
Length:734
Mass (Da):83,960
Last modified:October 11, 2004 - v3
Checksum:i6D0A2CCF57623179
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD65849.1.
PIRiT16182.
RefSeqiNP_494857.2. NM_062456.3.
UniGeneiCel.15305.

Genome annotation databases

EnsemblMetazoaiF26G1.6; F26G1.6; WBGene00017842.
GeneIDi173824.
KEGGicel:CELE_F26G1.6.
UCSCiF26G1.6. c. elegans.

Entry informationi

Entry nameiQ19831_CAEEL
AccessioniPrimary (citable) accession number: Q19831
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported