ID   MCP_IIV3                Reviewed;         466 AA.
AC   Q197E6;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   22-FEB-2023, entry version 49.
DE   RecName: Full=Major capsid protein;
DE            Short=MCP;
GN   Name=MCP; ORFNames=IIV3-014L;
OS   Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Chloriridovirus.
OX   NCBI_TaxID=345201;
OH   NCBI_TaxID=7163; Aedes vexans (Inland floodwater mosquito) (Culex vexans).
OH   NCBI_TaxID=42431; Culex territans.
OH   NCBI_TaxID=332058; Culiseta annulata.
OH   NCBI_TaxID=310513; Ochlerotatus sollicitans (eastern saltmarsh mosquito).
OH   NCBI_TaxID=329105; Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus).
OH   NCBI_TaxID=7183; Psorophora ferox.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16912294; DOI=10.1128/jvi.00464-06;
RA   Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A.,
RA   Kutish G.F., Rock D.L.;
RT   "Genome of invertebrate iridescent virus type 3 (mosquito iridescent
RT   virus).";
RL   J. Virol. 80:8439-8449(2006).
CC   -!- FUNCTION: Major capsid protein that self assembles to form an
CC       icosahedral capsid. Represents around 50% of the total virion protein
CC       mass (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NCLDV major capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; DQ643392; ABF82044.1; -; Genomic_DNA.
DR   RefSeq; YP_654586.1; NC_008187.1.
DR   SMR; Q197E6; -.
DR   GeneID; 4156263; -.
DR   KEGG; vg:4156263; -.
DR   OrthoDB; 5386at10239; -.
DR   Proteomes; UP000001358; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 2.70.9.10; Adenovirus Type 2 Hexon, domain 4; 1.
DR   Gene3D; 2.70.9.20; Major capsid protein Vp54; 1.
DR   InterPro; IPR031654; Capsid_N.
DR   InterPro; IPR007542; MCP_C.
DR   InterPro; IPR038519; MCP_C_sf.
DR   InterPro; IPR016112; VP_dsDNA_II.
DR   Pfam; PF16903; Capsid_N; 1.
DR   Pfam; PF04451; Capsid_NCLDV; 1.
DR   SUPFAM; SSF49749; Group II dsDNA viruses VP; 2.
PE   3: Inferred from homology;
KW   Capsid protein; Late protein; Reference proteome; Virion.
FT   CHAIN           1..466
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000377514"
SQ   SEQUENCE   466 AA;  50988 MW;  185217725541C253 CRC64;
     MSSSITSGFI DLATVDEIEK YMYGLPDDGV SMAHTLTYFV REFKKSTWFT QVPVPLSRST
     GTSDFGQNWS VSISRAGDYL LQTWLRVTIP QVTLAATATP ATLSLRWTRN LMHNLIREIT
     ISFNDLVGSR LDNYFLDMWS AFTTPASKRN GYDNMIGNIS TLTDPVGPGG SLGHTGGTVL
     NLPISLFFTR DTGVSLPTAA LPYNEIQLNF SMRDWKDLLI LTDTAITTGN PYQTIDVSKH
     LGGVAPSLSN VQVWANYAIV SNVERKKMGC GVRDILIEQV QTAPRQNYTP STNPMPSFDI
     RFSHAVKVLF FAVRNKTSAA EWSNYGTSSP VVSGTSVNYE PSGSFDPIAT TTLIYENSNR
     LGTMGSDYYS LVSPWYHAPT IPSFIGYHMY SYSLNFFDLD PMGSTNYGKL TNVSIVPHAS
     DAAVKASTGA GDGAGANYNQ SYEFIVMAVN NNIVRISGGC LGFPVL
//