Q197E6 (MCP_IIV3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Major capsid protein
Short name=MCP

Gene names

Name:	MCP
ORF Names:	IIV3-014L

Organism

Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) [Reference proteome]

Taxonomic identifier

345201 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Chloriridovirus

Virus host

Aedes vexans (Inland floodwater mosquito) (Culex vexans) [TaxID: 7163]
Culex territans [TaxID: 42431]
Culiseta annulata [TaxID: 332058]
Ochlerotatus sollicitans (eastern saltmarsh mosquito) [TaxID: 310513]
Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus) [TaxID: 329105]
Psorophora ferox [TaxID: 7183]

Protein attributes

Sequence length	466 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass By similarity.
Subunit structure	Homotrimer By similarity.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the NCLDV major capsid protein family.

Ontologies

Keywords
Cellular component	Virion
Developmental stage	Late protein
Molecular function	Capsid protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 466	466	Major capsid protein		PRO_0000377514

Sequences

	Sequence		Length	Mass (Da)
	Q197E6 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 185217725541C253	FASTA	466	50,988
	10 20 30 40 50 60 MSSSITSGFI DLATVDEIEK YMYGLPDDGV SMAHTLTYFV REFKKSTWFT QVPVPLSRST 70 80 90 100 110 120 GTSDFGQNWS VSISRAGDYL LQTWLRVTIP QVTLAATATP ATLSLRWTRN LMHNLIREIT 130 140 150 160 170 180 ISFNDLVGSR LDNYFLDMWS AFTTPASKRN GYDNMIGNIS TLTDPVGPGG SLGHTGGTVL 190 200 210 220 230 240 NLPISLFFTR DTGVSLPTAA LPYNEIQLNF SMRDWKDLLI LTDTAITTGN PYQTIDVSKH 250 260 270 280 290 300 LGGVAPSLSN VQVWANYAIV SNVERKKMGC GVRDILIEQV QTAPRQNYTP STNPMPSFDI 310 320 330 340 350 360 RFSHAVKVLF FAVRNKTSAA EWSNYGTSSP VVSGTSVNYE PSGSFDPIAT TTLIYENSNR 370 380 390 400 410 420 LGTMGSDYYS LVSPWYHAPT IPSFIGYHMY SYSLNFFDLD PMGSTNYGKL TNVSIVPHAS 430 440 450 460 DAAVKASTGA GDGAGANYNQ SYEFIVMAVN NNIVRISGGC LGFPVL

References

[1]	"Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)." Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L. J. Virol. 80:8439-8449(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ643392 Genomic DNA. Translation: ABF82044.1.
RefSeq	YP_654586.1. NC_008187.1.
3D structure databases
ProteinModelPortal	Q197E6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4156263.
Phylogenomic databases
ProtClustDB	CLSP2511135.
Family and domain databases
Gene3D	2.70.9.10. 1 hit. 2.70.9.20. 1 hit.
InterPro	IPR016114. ASFV_p72. IPR016111. Hexon_subdom4. IPR016112. Virus_hexon. IPR007542. Virus_major_coat_C. [Graphical view]
Pfam	PF04451. Capsid_NCLDV. 1 hit. [Graphical view]
SUPFAM	SSF49749. Coat_hexon/vp54/p3_dsDNA-vir. 2 hits.
ProtoNet	Search...

Entry information

Entry name

MCP_IIV3

Accession

Primary (citable) accession number: Q197E6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2009
Last sequence update:	July 11, 2006
Last modified:	March 6, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program