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Protein

Major capsid protein

Gene

MCP

Organism
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass (By similarity).By similarity

GO - Molecular functioni

  1. structural molecule activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein
Short name:
MCP
Gene namesi
Name:MCP
ORF Names:IIV3-014L
OrganismiInvertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
Taxonomic identifieri345201 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeChloriridovirus
Virus hostiAedes vexans (Inland floodwater mosquito) (Culex vexans) [TaxID: 7163]
Culex territans [TaxID: 42431]
Culiseta annulata [TaxID: 332058]
Ochlerotatus sollicitans (eastern saltmarsh mosquito) [TaxID: 310513]
Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus) [TaxID: 329105]
Psorophora ferox [TaxID: 7183]
ProteomesiUP000001358 Componenti: Genome

Subcellular locationi

  1. Virion Curated

GO - Cellular componenti

  1. viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Major capsid proteinPRO_0000377514Add
BLAST

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Homotrimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ197E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NCLDV major capsid protein family.Curated

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.

Sequencei

Sequence statusi: Complete.

Q197E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSITSGFI DLATVDEIEK YMYGLPDDGV SMAHTLTYFV REFKKSTWFT
60 70 80 90 100
QVPVPLSRST GTSDFGQNWS VSISRAGDYL LQTWLRVTIP QVTLAATATP
110 120 130 140 150
ATLSLRWTRN LMHNLIREIT ISFNDLVGSR LDNYFLDMWS AFTTPASKRN
160 170 180 190 200
GYDNMIGNIS TLTDPVGPGG SLGHTGGTVL NLPISLFFTR DTGVSLPTAA
210 220 230 240 250
LPYNEIQLNF SMRDWKDLLI LTDTAITTGN PYQTIDVSKH LGGVAPSLSN
260 270 280 290 300
VQVWANYAIV SNVERKKMGC GVRDILIEQV QTAPRQNYTP STNPMPSFDI
310 320 330 340 350
RFSHAVKVLF FAVRNKTSAA EWSNYGTSSP VVSGTSVNYE PSGSFDPIAT
360 370 380 390 400
TTLIYENSNR LGTMGSDYYS LVSPWYHAPT IPSFIGYHMY SYSLNFFDLD
410 420 430 440 450
PMGSTNYGKL TNVSIVPHAS DAAVKASTGA GDGAGANYNQ SYEFIVMAVN
460
NNIVRISGGC LGFPVL
Length:466
Mass (Da):50,988
Last modified:July 11, 2006 - v1
Checksum:i185217725541C253
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ643392 Genomic DNA. Translation: ABF82044.1.
RefSeqiYP_654586.1. NC_008187.1.

Genome annotation databases

GeneIDi4156263.
KEGGivg:4156263.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ643392 Genomic DNA. Translation: ABF82044.1.
RefSeqiYP_654586.1. NC_008187.1.

3D structure databases

ProteinModelPortaliQ197E6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4156263.
KEGGivg:4156263.

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)."
    Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L.
    J. Virol. 80:8439-8449(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiMCP_IIV3
AccessioniPrimary (citable) accession number: Q197E6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: July 11, 2006
Last modified: April 1, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.