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Protein
Submitted name:

DEGenerin-related Touch-involved channel

Gene

degt-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Submitted name:
DEGenerin-related Touch-involved channelImported
Gene namesi
Name:degt-1Imported
ORF Names:CELE_F25D1.4Imported, F25D1.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF25D1.4; CE45781; WBGene00009109; degt-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei63 – 8422HelicalSequence analysisAdd
BLAST
Transmembranei808 – 83831HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ19777.
PRIDEiQ19777.

Interactioni

Protein-protein interaction databases

STRINGi6239.F25D1.4.

Structurei

3D structure databases

ProteinModelPortaliQ19777.
SMRiQ19777. Positions 770-832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00730000114192.
HOGENOMiHOG000199557.
InParanoidiQ19777.
OMAiWERITTY.
OrthoDBiEOG72VH5P.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 2 hits.
PfamiPF00858. ASC. 2 hits.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

Q19777-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRKRRSEDV DAMVIATSPI KIKVEQFIEE TSSMDVYIPA LDRFAEDTSM
60 70 80 90 100
LGFRYLHTRY KTWFRVLWGF VVVFFIGLTF YQVFERVTYY FIKNPLTTRR
110 120 130 140 150
SYETLPNMYF PTIGVCNKMQ IKASSVASKN PDLLRGMCSV LDESSSNSSR
160 170 180 190 200
FDELDKFDDV DILSLYRNSF QSADDLFVSC EFGKSGSCQD EIRPIYTPFG
210 220 230 240 250
LCYSVSPNKT ILRPGPETTL SLVLNLEVHE IIPGTVVEPG VVLSIYDGAS
260 270 280 290 300
SLSHYSEGIH LEAGKVVTIP VNEVRKLRLH ESSCGSTKME SFSEKEYSKA
310 320 330 340 350
ACEWSVSVKQ IEKECGCIPI RNPIYRGVFD NKNDPLNNST EIPKKKYKKW
360 370 380 390 400
KKRNIPRCTL RQEIECVQEK LNIRPHIDDS ICPDDCDDIS FSSIVFGGKL
410 420 430 440 450
SSSEIVSMLP SDWEDTKEKR VADYQKVLEV IPNKMIPVVR NVQQLADELQ
460 470 480 490 500
LFVKEASEIF GVSDNFHDVK CLSLDGRTYE SFINQFYSYE PTWERITTYL
510 520 530 540 550
QHSLARELNS TALCLGLFLT EKGEIDDTVT PVVNMTLASI SLLQLGQIEN
560 570 580 590 600
SLGKANFNYG LTMMHESTRR VVLGLAHPLI TEVRDCVTKM YENLERVEEI
610 620 630 640 650
AEDCRIIFKN RYTPLIEASN VHTKTNPNSE SFKLYTEAMK KVLAKLQILK
660 670 680 690 700
TRVRMSEWKD FKIDLKEFES SYREIAKDHV EIEEMLKLRK TMVTDIPALA
710 720 730 740 750
NELSETFLAA TESRRKFAVL TGIAADESFS DKFSNFSKCL DELHEKAPNL
760 770 780 790 800
KKTRFIRGEW LSRLRNQVLM AQSYSPTPQY DVVNLLHIKF YFAHFKQETI
810 820 830 840 850
LQERSYNLFL LLAEIGGTIG LYVGATLLTA AETLVFLCER KKSNIFLKPQ

FI
Length:852
Mass (Da):97,689
Last modified:April 5, 2011 - v3
Checksum:i949338304DBAD980
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAA98267.3.
RefSeqiNP_505703.3. NM_073302.3.
UniGeneiCel.3905.

Genome annotation databases

EnsemblMetazoaiF25D1.4; F25D1.4; WBGene00009109.
GeneIDi184921.
KEGGicel:CELE_F25D1.4.
UCSCiF25D1.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAA98267.3.
RefSeqiNP_505703.3. NM_073302.3.
UniGeneiCel.3905.

3D structure databases

ProteinModelPortaliQ19777.
SMRiQ19777. Positions 770-832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F25D1.4.

Proteomic databases

PaxDbiQ19777.
PRIDEiQ19777.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF25D1.4; F25D1.4; WBGene00009109.
GeneIDi184921.
KEGGicel:CELE_F25D1.4.
UCSCiF25D1.4. c. elegans.

Organism-specific databases

CTDi184921.
WormBaseiF25D1.4; CE45781; WBGene00009109; degt-1.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00730000114192.
HOGENOMiHOG000199557.
InParanoidiQ19777.
OMAiWERITTY.
OrthoDBiEOG72VH5P.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 2 hits.
PfamiPF00858. ASC. 2 hits.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ19777_CAEEL
AccessioniPrimary (citable) accession number: Q19777
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: April 5, 2011
Last modified: June 8, 2016
This is version 106 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.