Reviewed,
UniProtKB/Swiss-Prot Q196X0 (RPB1_IIV3)
Last modified
January 19, 2010.
Version 29.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Probable DNA-directed RNA polymerase II subunit RPB1 homolog EC=2.7.7.6 | ||
| Gene names |
| ||
| Organism | Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) | ||
| Taxonomic identifier | 345201 [NCBI] | ||
| Taxonomic lineage | Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Chloriridovirus | ||
| Virus host | Aedes vexans (Inland floodwater mosquito) (Culex vexans) [TaxID: 7163] Psorophora ferox [TaxID: 7183] Culex territans [TaxID: 42431] Ochlerotatus sollicitans (eastern saltmarsh mosquito) [TaxID: 310513] Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus) [TaxID: 329105] Culiseta annulata [TaxID: 332058] |
Protein attributes
| Sequence length | 1377 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit By similarity. |
| Catalytic activity | Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). |
| Sequence similarities | Belongs to the RNA polymerase beta' chain family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription |
| Cellular component | DNA-directed RNA polymerase |
| Ligand | Magnesium Metal-binding Zinc |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome Virus reference strain |
| Gene Ontology (GO) | |
| Biological process | transcription Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activityInferred from electronic annotation. Source: UniProtKB-KW magnesium ion bindingInferred from electronic annotation. Source: UniProtKB-KW zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 1377 | 1377 | Probable DNA-directed RNA polymerase II subunit RPB1 homolog | PRO_0000377494 | |||||
Sites | |||||||||
| Metal binding | 57 | 1 | Zinc 1 By similarity | ||||||
| Metal binding | 60 | 1 | Zinc 1 By similarity | ||||||
| Metal binding | 67 | 1 | Zinc 1 By similarity | ||||||
| Metal binding | 70 | 1 | Zinc 1 By similarity | ||||||
| Metal binding | 97 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 100 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 132 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 493 | 1 | Magnesium; catalytic By similarity | ||||||
| Metal binding | 495 | 1 | Magnesium; catalytic By similarity | ||||||
| Metal binding | 497 | 1 | Magnesium; catalytic By similarity | ||||||
Sequences
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References
| [1] | "Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)." Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L. J. Virol. 80:8439-8449(2006) [PubMed: 16912294] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | DQ643392 Genomic DNA. Translation: ABF82120.1. |
| RefSeq | YP_654662.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4156234. |
Family and domain databases | |
| InterPro | IPR000722. RNA_pol_asu. IPR006592. RNA_pol_N. IPR007080. RNA_pol_Rpb1_1. IPR007066. RNA_pol_Rpb1_3. IPR007083. RNA_pol_Rpb1_4. IPR007081. RNA_pol_Rpb1_5. [Graphical view] |
| Gene3D | G3DSA:2.40.40.30. RNA_pol_A. 1 hit. G3DSA:3.90.1120.10. RNA_pol_Rpb1_1. 1 hit. |
| Pfam | PF04997. RNA_pol_Rpb1_1. 2 hits. PF00623. RNA_pol_Rpb1_2. 1 hit. PF04983. RNA_pol_Rpb1_3. 1 hit. PF05000. RNA_pol_Rpb1_4. 1 hit. PF04998. RNA_pol_Rpb1_5. 1 hit. [Graphical view] |
| SMART | SM00663. RPOLA_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RPB1_IIV3 | ||||||||
| Accession | Primary (citable) accession number: Q196X0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Virus (Virus annotation project) | ||||||||
