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Q196W4 (VF347_IIV3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length148 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation By similarity.

Catalytic activity

2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.

Cofactor

FAD By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the IIV-6 347L family.

Contains 1 ERV/ALR sulfhydryl oxidase domain.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   PTMDisulfide bond
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionthiol oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 148148Putative FAD-linked sulfhydryl oxidase 096R
PRO_0000377497

Regions

Transmembrane122 – 14221Helical; Potential
Domain1 – 103103ERV/ALR sulfhydryl oxidase
Compositional bias111 – 1144Poly-Ala
Compositional bias135 – 1384Poly-Val

Amino acid modifications

Disulfide bond48 ↔ 51Redox-active Potential

Sequences

Sequence LengthMass (Da)Tools
Q196W4 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 55AA1099C22FAB39

FASTA14816,744
        10         20         30         40         50         60 
MSIDPKLWGN AFWSTLHHVA AGYNDHPSLG ARQVMTNFIQ SIPVLLPCAE CQDHAFDYIG 

        70         80         90        100        110        120 
RADLDRVVSS RRQLFLFFFN FHNHVNARLN KPQLAAKTVF QRYRVPFDGE AAAATTEPPF 

       130        140 
HWSPWLTTAL AVILVVVVAG IGHRSRFK 

« Hide

References

[1]"Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)."
Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L.
J. Virol. 80:8439-8449(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ643392 Genomic DNA. Translation: ABF82126.1.
RefSeqYP_654668.1. NC_008187.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4156240.

Family and domain databases

Gene3D1.20.120.310. 1 hit.
InterProIPR017905. ERV/ALR_sulphydryl_oxidase.
[Graphical view]
PfamPF04777. Evr1_Alr. 1 hit.
[Graphical view]
SUPFAMSSF69000. SSF69000. 1 hit.
PROSITEPS51324. ERV_ALR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVF347_IIV3
AccessionPrimary (citable) accession number: Q196W4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: July 11, 2006
Last modified: May 14, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families