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Q196W4

- VF347_IIV3

UniProt

Q196W4 - VF347_IIV3

Protein

Putative FAD-linked sulfhydryl oxidase 096R

Gene

IIV3-096R

Organism
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.PROSITE-ProRule annotation

    Catalytic activityi

    2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.

    Cofactori

    FAD.PROSITE-ProRule annotation

    GO - Molecular functioni

    1. thiol oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative FAD-linked sulfhydryl oxidase 096R (EC:1.8.3.2)
    Gene namesi
    ORF Names:IIV3-096R
    OrganismiInvertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
    Taxonomic identifieri345201 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeChloriridovirus
    Virus hostiAedes vexans (Inland floodwater mosquito) (Culex vexans) [TaxID: 7163]
    Culex territans [TaxID: 42431]
    Culiseta annulata [TaxID: 332058]
    Ochlerotatus sollicitans (eastern saltmarsh mosquito) [TaxID: 310513]
    Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus) [TaxID: 329105]
    Psorophora ferox [TaxID: 7183]
    ProteomesiUP000001358: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 148148Putative FAD-linked sulfhydryl oxidase 096RPRO_0000377497Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi48 ↔ 51Redox-activePROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei122 – 14221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 103103ERV/ALR sulfhydryl oxidasePROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi111 – 1144Poly-Ala
    Compositional biasi135 – 1384Poly-Val

    Sequence similaritiesi

    Belongs to the IIV-6 347L family.Curated
    Contains 1 ERV/ALR sulfhydryl oxidase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    Gene3Di1.20.120.310. 1 hit.
    InterProiIPR017905. ERV/ALR_sulphydryl_oxidase.
    [Graphical view]
    PfamiPF04777. Evr1_Alr. 1 hit.
    [Graphical view]
    SUPFAMiSSF69000. SSF69000. 1 hit.
    PROSITEiPS51324. ERV_ALR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q196W4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIDPKLWGN AFWSTLHHVA AGYNDHPSLG ARQVMTNFIQ SIPVLLPCAE    50
    CQDHAFDYIG RADLDRVVSS RRQLFLFFFN FHNHVNARLN KPQLAAKTVF 100
    QRYRVPFDGE AAAATTEPPF HWSPWLTTAL AVILVVVVAG IGHRSRFK 148
    Length:148
    Mass (Da):16,744
    Last modified:July 11, 2006 - v1
    Checksum:i55AA1099C22FAB39
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ643392 Genomic DNA. Translation: ABF82126.1.
    RefSeqiYP_654668.1. NC_008187.1.

    Genome annotation databases

    GeneIDi4156240.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ643392 Genomic DNA. Translation: ABF82126.1 .
    RefSeqi YP_654668.1. NC_008187.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4156240.

    Family and domain databases

    Gene3Di 1.20.120.310. 1 hit.
    InterProi IPR017905. ERV/ALR_sulphydryl_oxidase.
    [Graphical view ]
    Pfami PF04777. Evr1_Alr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69000. SSF69000. 1 hit.
    PROSITEi PS51324. ERV_ALR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)."
      Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L.
      J. Virol. 80:8439-8449(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiVF347_IIV3
    AccessioniPrimary (citable) accession number: Q196W4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3