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Protein

Putative ribonuclease 3

Gene

IIV3-101R

Organism
Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.

GO - Molecular functioni

  1. ribonuclease III activity Source: UniProtKB-EC
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribonuclease 3 (EC:3.1.26.3)
Gene namesi
ORF Names:IIV3-101R
OrganismiInvertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus)
Taxonomic identifieri345201 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeChloriridovirus
Virus hostiAedes vexans (Inland floodwater mosquito) (Culex vexans) [TaxID: 7163]
Culex territans [TaxID: 42431]
Culiseta annulata [TaxID: 332058]
Ochlerotatus sollicitans (eastern saltmarsh mosquito) [TaxID: 310513]
Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus) [TaxID: 329105]
Psorophora ferox [TaxID: 7183]
ProteomesiUP000001358 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 333333Putative ribonuclease 3PRO_0000376953Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini81 – 208128RNase IIIPROSITE-ProRule annotationAdd
BLAST
Domaini250 – 31970DRBMAdd
BLAST

Sequence similaritiesi

Belongs to the IIV-6 142R family.Curated
Contains 1 RNase III domain.PROSITE-ProRule annotation

Phylogenomic databases

KOiK03685.

Family and domain databases

Gene3Di1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000999. RNase_III_dom.
[Graphical view]
PfamiPF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 1 hit.
PROSITEiPS50142. RNASE_3_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q196V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVCTNRPPV SPVLQLCRFA SNVVLFHLKI VKQIKFEFLN VFNLKIKRLQ
60 70 80 90 100
METEVYYGPR DDSFKDFLIK IFKLMDMGST RSETSNFLNT YINEETLPYF
110 120 130 140 150
NMAFTSSSAN ELNNYELFEQ MGDSTIGKFI VWSSYEKFPQ LRGKPEAVEI
160 170 180 190 200
VARMKINLGS KDNLSQIAED LGMWTFISAT EEARHRLKKK LLEDVFEALI
210 220 230 240 250
GVTEYIIYEF TDTNYSQPGL AYQLVYSLLL KLFDPYILKI DYNTLVDSKN
260 270 280 290 300
RLKGVFDQYK DKLGLQPVYQ SERIVKNDKN VFLSKVYDGN GNFLGEGTAP
310 320 330
LKKEAEKKAS EVAILTLISN GYKKNIPSLY ETL
Length:333
Mass (Da):38,408
Last modified:July 11, 2006 - v1
Checksum:i721A2F2A2FD5B4C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ643392 Genomic DNA. Translation: ABF82131.1.
RefSeqiYP_654673.1. NC_008187.1.

Genome annotation databases

GeneIDi4156245.
KEGGivg:4156245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ643392 Genomic DNA. Translation: ABF82131.1.
RefSeqiYP_654673.1. NC_008187.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4156245.
KEGGivg:4156245.

Phylogenomic databases

KOiK03685.

Family and domain databases

Gene3Di1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000999. RNase_III_dom.
[Graphical view]
PfamiPF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 1 hit.
PROSITEiPS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus)."
    Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A., Kutish G.F., Rock D.L.
    J. Virol. 80:8439-8449(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiRNC_IIV3
AccessioniPrimary (citable) accession number: Q196V9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: July 11, 2006
Last modified: April 1, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.